Evidence map›Paper›PMID 34956362›Full record

ArticleGastroenterology research and practice2021

Risk of Bleeding after Colorectal Endoscopic Resection in Patients with Continued Warfarin Use Compared to Heparin Replacement: A Propensity Score Matching Analysis.

Katsuaki Inagaki, Ken Yamashita, Shiro Oka, Fumiaki Tanino, Noriko Yamamoto, Yuki Kamigaichi, Hirosato Tamari, Yasutsugu Shimohara, Tomoyuki Nishimura, Yuki Okamoto and 7 more

Open access · goldAbstract read
In one paragraph

Article in Gastroenterology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. [IDEN Consensus on Management of Antithrombotic Agents in Patients Undergoing Gastrointestinal Endoscopy].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Katsuaki InagakiDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Ken YamashitaDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Shiro OkaDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.ORCID https://orcid.org/0000-0002-1652-0743
Fumiaki TaninoDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Noriko YamamotoDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Yuki KamigaichiDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Hirosato TamariDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Yasutsugu ShimoharaDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Tomoyuki NishimuraDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Yuki OkamotoDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, Hiroshima, Japan.
Hidenori TanakaDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Takahiro KotachiDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Ryo YugeDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Yuji UrabeDivision of Regeneration and Medicine Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.
Yasuhiko KitadaiFaculty of Human Culture and Science, Department of Health Sciences, Prefectural University of Hiroshima, Hiroshima, Japan.
Kenichi YoshimuraMedical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan.
Shinji TanakaDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Hiroshima University Hospital · JPPrefectural University of Hiroshima · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Japan Gastroenterological Endoscopy Society (JGES) guidelines recommend continued warfarin treatment during gastroenterological endoscopic procedures with a high risk of bleeding as an alternative to heparin replacement in patients on warfarin therapy. However, there is insufficient evidence to support the use of warfarin in colorectal endoscopic resection (ER). The present study is aimed at verifying the risk of bleeding after ER for colorectal neoplasia (CRN) in patients with continued warfarin use. This was a single-center retrospective cohort study using clinical records. We assessed 126 consecutive patients with 159 CRNs who underwent ER (endoscopic mucosal resection, 146 cases; endoscopic submucosal dissection, 13 cases) at Hiroshima University Hospital between January 2014 and December 2019. Patients were divided into two groups: the heparin replacement group (79 patients with 79 CRNs) and the continued warfarin group (47 patients with 80 CRNs). One-to-one propensity score matching was performed to compare the bleeding rate after ER between the groups. The rate of bleeding after ER was significantly higher in the heparin replacement group than in the continued warfarin group for both before (10.1% vs. 1.3%, respectively;

Identifiers

PMID34956362
PMCPMC8709771
OpenAlexW4200227334

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.