Evidence map›Paper›PMID 34956307›Full record

ArticleFrontiers in genetics2021

Validating a Genomic Convergence and Network Analysis Approach Using Association Analysis of Identified Candidate Genes in Alzheimer's Disease.

Puneet Talwar, Suman Kushwaha, Chitra Rawat, Harpreet Kaur, Ankit Srivastava, Rachna Agarwal, Puneet Chandna, Paolo Tucci, Luciano Saso, Ritushree Kukreti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Puneet TalwarGenomics and Molecular Medicine Unit, Institute of Genomics and Integrative Biology (IGIB), Council of Scientific and Industrial Research (CSIR), Delhi, India.
Suman KushwahaInstitute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India.
Chitra RawatGenomics and Molecular Medicine Unit, Institute of Genomics and Integrative Biology (IGIB), Council of Scientific and Industrial Research (CSIR), Delhi, India.
Harpreet KaurGenomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, United States.
Ankit SrivastavaGenomics and Molecular Medicine Unit, Institute of Genomics and Integrative Biology (IGIB), Council of Scientific and Industrial Research (CSIR), Delhi, India.
Rachna AgarwalInstitute of Human Behaviour and Allied Sciences (IHBAS), Delhi, India.
Puneet ChandnaAceProbe Technologies (India) Pvt. Ltd, Delhi, India.
Paolo TucciDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Luciano SasoDepartment of Physiology and Pharmacology "Vittorio Erspamer" Sapienza University, Rome, Italy.
Ritushree KukretiGenomics and Molecular Medicine Unit, Institute of Genomics and Integrative Biology (IGIB), Council of Scientific and Industrial Research (CSIR), Delhi, India.
Institute of Genomics and Integrative Biology · INInstitute of Human Behaviour and Allied Sciences · INAcademy of Scientific and Innovative Research · INCleveland Clinic · USCouncil of Scientific and Industrial Research · INUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previously, we demonstrated an integrated genomic convergence and network analysis approach to identify the candidate genes associated with the complex neurodegenerative disorder, Alzheimer's disease (AD). Here, we performed a pilot study to validate the

Indexed as

ACTBAlzheimer’s diseaseAPOEEGFRgeneticssingle-nucleotide polymorphism (SNP)

Identifiers

PMID34956307
PMCPMC8696000
OpenAlexW4200539111

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.