Evidence map›Paper›PMID 34956227›Full record

ArticleFrontiers in immunology2021

IL-15Rα-Independent IL-15 Signaling in Non-NK Cell-Derived IFNγ Driven Control of

Madhuparna Nandi, Mitterrand Muamba Moyo, Sakina Orkhis, Jeanne Masunga Faida Mobulakani, Marc-André Limoges, Fjolla Rexhepi, Marian Mayhue, Anny Armas Cayarga, Gisela Cofino Marrero, Subburaj Ilangumaran and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Madhuparna NandiDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Mitterrand Muamba MoyoDepartment of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
Sakina OrkhisDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Jeanne Masunga Faida MobulakaniDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Marc-André LimogesDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Fjolla RexhepiDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Marian MayhueDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Anny Armas CayargaDepartment of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
Gisela Cofino MarreroDepartment of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
Subburaj IlangumaranDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Alfredo MenendezDepartment of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC, Canada.
Sheela RamanathanDepartment of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, QC, Canada.
Université de Sherbrooke · CACentre Hospitalier Universitaire de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-15, produced by hematopoietic and parenchymal cells, maintains immune cell homeostasis and facilitates activation of lymphoid and myeloid cell subsets. IL-15 interacts with the ligand-binding receptor chain IL-15Rα during biosynthesis, and the IL-15:IL-15Rα complex is trans-presented to responder cells that express the IL-2/15Rβγ

Indexed as

AnimalsCells, CulturedCytokinesHumansInflammation MediatorsInterferon-gammaInterleukin-15Listeria monocytogenesListeriosisMacrophagesMiceMice, Inbred C57BLMice, KnockoutNitric Oxide Synthase Type IIPhagocytosisReceptors, Interleukin-15CytokinesInflammation MediatorsInterferon-gammaInterleukin-15Nitric Oxide Synthase Type IIReceptors, Interleukin-15IFN-gammaIL-15IL-15 Receptor alphainfectionListeriamicespleen

Identifiers

PMID34956227
PMCPMC8703170
OpenAlexW4200191401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.