Evidence map›Paper›PMID 34956182›Full record

ArticleFrontiers in immunology2021

Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection.

Praveen M Varghese, Shuvechha Mukherjee, Futwan A Al-Mohanna, Souad M Saleh, Fahad N Almajhdi, Nazar Beirag, Saad H Alkahtani, Reena Rajkumari, Beatrice Nal Rogier, Robert B Sim and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Innate Immune Response to Viral Infection.Advances in experimental medicine and biology · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. The Immunosuppressive Roles of PD-L1 during Influenza A Virus Infection.International journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Praveen M VargheseBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Shuvechha MukherjeeBiomedical Informatics Centre, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India.
Futwan A Al-MohannaDepartment of Cell Biology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Souad M SalehDepartment of Cell Biology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Fahad N AlmajhdiDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Nazar BeiragBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Saad H AlkahtaniDepartment of Zoology, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Reena RajkumariSchool of Biosciences and Technology, Vellore Institute of Technology, Vellore, India.
Beatrice Nal RogierINSERM U1104 Centre d'immunologie de Marseille-Luminy (CIML), Marseille, France.
Robert B SimDepartment of Biochemistry, University of Oxford, Oxford, United Kingdom.
Susan Idicula-ThomasBiomedical Informatics Centre, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India.
Taruna MadanDepartment of Innate Immunity, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health, Mumbai, India.
Valarmathy MurugaiahBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Uday KishoreBiosciences, College of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Brunel University of London · GBNational Institute for Research in Reproductive Health · INKing Faisal Specialist Hospital & Research Centre · SAKing Saud University · SACentre d’Immunologie de Marseille-Luminy · FRUniversity of Oxford · GBVellore Institute of Technology University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system is designed to recognise and eliminate invading pathogens

Indexed as

AnimalsDogsHumansInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza, HumanMadin Darby Canine Kidney CellsNeutrophilsProperdinProperdincomplement evasioncomplement systemcytokine stormhuman properdininfluenza A virusinnate immune systemRNA viruses

Identifiers

PMID34956182
PMCPMC8695448
OpenAlexW4200538012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.