Evidence map›Paper›PMID 34956095›Full record

Observational studyFrontiers in endocrinology2021

Association Between the Triglyceride-Glucose Index and the Incidence of Diabetes in People With Different Phenotypes of Obesity: A Retrospective Study.

Su Zou, Chenxi Yang, Rui Shen, Xiang Wei, Junwen Gong, Yali Pan, Yang Lv, Yingjia Xu

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

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  17. Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Su ZouDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Chenxi YangDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Rui ShenDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Xiang WeiDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Junwen GongDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Yali PanDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Yang LvDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Yingjia XuDepartment of Cardiology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: We aimed to examine the relationship between the Triglyceride-glucose (TyG) index and the incidence of type 2 diabetes in people with different phenotypes of obesity. Methods: From May 1, 1994 to December 31, 2016, 15,464 participants were enrolled in the medical examination program at the Murakami Memorial Hospital to determine the relationship between the TyG index and the incidence of type 2 diabetes in people with different phenotypes of obesity after 5.38 years of follow-up. Results: Besides triglycerides, HbA1c%, and FPG, the incidence of type 2 diabetes was found to be significantly associated with the TyG index (p <0.001), age (p <0.001), BMI (p = 0.033), current smoker (p <0.001), and fatty liver (p <0.001). In participants with visceral fat obesity and/or ectopic fat obesity and normal BMI, the TyG index was significantly associated with the incidence of type 2 diabetes after adjusting for confounding factors. In patients with BMI ≥25 mg/m Conclusion: In participants with obesity involving visceral fat obesity and/or fatty liver and normal BMI which is not a measure of body fat distribution, there was a significant association between the TyG index and incidence of T2DM.

Indexed as

AdultBlood GlucoseDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansIncidenceJapanMaleMiddle AgedObesityPhenotypeRetrospective StudiesTriglyceridesBlood GlucoseTriglyceridesdiabetesinsulin resistanceobesityretrospective studyTyG index

Identifiers

PMID34956095
PMCPMC8695922
OpenAlexW4200298424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.