Evidence map›Paper›PMID 34955639›Full record

ArticleInternational journal of nanomedicine2021

Antiviral Activity of Zinc Oxide Nanoparticles Mediated by

Mina Michael Melk, Seham S El-Hawary, Farouk Rasmy Melek, Dalia Osama Saleh, Omar M Ali, Mohamed A El Raey, Nabil Mohamed Selim

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

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  14. RSC advances · 2024
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  20. Antiviral Activity of Zinc Oxide Nanoparticles against SARS-CoV-2.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mina Michael MelkPharmacognosy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.ORCID 0000-0001-5176-6258
Seham S El-HawaryPharmacognosy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.ORCID 0000-0002-6823-1142
Farouk Rasmy MelekChemistry of Natural Compounds Department, National Research Centre, Giza, Egypt.ORCID 0000-0002-9175-9850
Dalia Osama SalehPharmacology Department, National Research Centre, Giza, Egypt.ORCID 0000-0002-5401-5422
Omar M AliDepartment of Chemistry, Turabah University College, Turabah Branch, Taif University, Taif, 21944, Saudi Arabia.ORCID 0000-0002-2653-1542
Mohamed A El RaeyDepartment of Phytochemistry and Plant Systematics, Pharmaceutical Division, National Research Centre, Dokki, Cairo, Egypt.ORCID 0000-0002-5960-3012
Nabil Mohamed SelimPharmacognosy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.ORCID 0000-0001-6252-000X
Cairo University · EGNational Research Centre · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction

methodsZnONPs were described by the following techniques, UV-visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), zeta potential, scanning electron microscopy (SEM), transmission electron microscopy (TEM) and x-ray diffraction (XRD). The phenolic and flavonoid contents of

resultsDLS revealed that the average size of ZnONPs was 32.58 ± 7.98 nm and the zeta potential was -20.8 mV. The observation of TEM analysis revealed that the particle size of ZnONPs varied from 2.56 to 8.83 nm. The XRD analysis verified the existence of pure crystals of hexagonal shapes of nanoparticles of ZnO with a main average size of 35.28 nm that is approximating to the values of particle size acquired by SEM analysis (19.64 and 23.21 nm). The HPLC analysis of

conclusionThe green synthesized ZnONPs are considered promising adjuvants to enhance the efficacy of HSV-1 drugs.

Indexed as

Antiviral AgentsHerpesvirus 1, HumanMetal NanoparticlesPlumbaginaceaeZinc OxidePlant ExtractsAntiviral AgentsPlant ExtractsZinc Oxideantiviral activity and green synthesisHPLC analysisPlumbago indica L.ZnO nanoparticles

Identifiers

PMID34955639
PMCPMC8694278
OpenAlexW4200415876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.