Evidence map›Paper›PMID 34955445›Full record

ArticleJournal of geriatric oncology2022

Exploring and supporting older women's chemotherapy decision-making in early-stage breast cancer.

Meghan S Karuturi, Sharon H Giordano, Diana S Hoover, Robert J Volk, Ashley J Housten

Open access · greenAbstract read
In one paragraph

Article in Journal of geriatric oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Meghan S KaruturiDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address: mskaruturi@mdanderson.org.
Sharon H GiordanoDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States; Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Diana S HooverDepartment of Health Disparities Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Robert J VolkDepartment of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Ashley J HoustenDivision of Public Health Sciences, Washington University School of Medicine, St. Louis, MO, United States.
The University of Texas MD Anderson Cancer Center · USWashington University in St. Louis · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Developing a Decision Tool for Chemotherapy in Older Women with Early Stage Breast CancerK08CA241087 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KARUTURI, MEGHAN SRI · 2019 to 2024
$1.3M
Breast Cancer Screening: Priorities and Attitudes of Diverse Women Under 50R00MD011485 · NIMHD · WASHINGTON UNIVERSITY · PI HOUSTEN, ASHLEY · 2019 to 2021
$712k
Health Literacy and Smoking Cessation in Low-SES, Diverse SmokersK23DA040933 · NIDA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOOVER, DIANA STEWART · 2016 to 2018
$500k
Breast Cancer Screening: Priorities and Attitudes of Diverse Women Under 50K99MD011485 · NIMHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOUSTEN, ASHLEY · 2017 to 2018
$177k
NCI NIH HHS K08 CA241087NCI NIH HHS P30 CA016672NIDA NIH HHS K23 DA040933NIMHD NIH HHS K99 MD011485NIMHD NIH HHS R00 MD011485
6 · The paper itself

Abstract

backgroundFew studies have focused on the therapeutic decision-making process in older adults with breast cancer. This study investigated older adult breast cancer patients' perspectives on neo/adjuvant chemotherapy, thereby identifying informational needs and preferences as patients navigate the treatment decision-making process. MATERIALS AND

methodsWomen ≥65 years diagnosed with early-stage breast cancer were recruited from an academic cancer center after deciding whether or not to receive neo/adjuvant chemotherapy. Participants completed surveys assessing sociodemographic characteristics, health literacy/numeracy, and shared decision making. They took part in individual semi-structured interviews to explore their perspectives, experiences, and values regarding treatment. Interviews were audio-recorded and transcribed. Transcripts were analyzed using the Sort and Sift, Think and Shift qualitative approach. Quantitative data was summarized using descriptive statistics.

resultsOf the 26 participants (age range 65-92 years; 81% non-Hispanic White; 72% ≥ college degree; 50% unmarried), 58% elected to undergo chemotherapy and 42% declined. The majority of participants had adequate health literacy/numeracy and engaged in shared decision-making. Thematic analysis revealed several commonalities regardless of the decision to undergo chemotherapy. Participants sought information regarding their disease/treatment. They referenced subjective experiences of friends/family members with cancer. Self-perception of health and the side effects of chemotherapy were also key factors. Participants placed importance on the maintenance of quality of life throughout treatment.

conclusionsDecision-making strategies in older patients were shaped by knowledge, values, and the anecdotal experiences of others. Results can inform the development of decision support tools for older patients and physicians to better facilitate the shared decision-making process.

Indexed as

Breast NeoplasmsAgedAged, 80 and overChemotherapy, AdjuvantDecision MakingDecision Making, SharedFemaleHumansQualitative ResearchQuality of LifeBreast cancerChemotherapyDecision-makingGeriatric oncologyQualitative designShared decision-making

Identifiers

PMID34955445
PMCPMC9045544
OpenAlexW4200097375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.