Evidence map›Paper›PMID 34955379›Full record

ArticleExplore (New York, N.Y.)

Integrated Chinese herbal medicine and Western medicine successfully resolves spontaneous subcutaneous emphysema and pneumomediastinum in a patient with severe COVID-19 in Taiwan: A case report.

Shuo-Wen Hung, Yuan-Ching Liao, I-Chang Chi, Ting-Yen Lin, Yu-Chuan Lin, Hung-Jen Lin, Sheng-Teng Huang

Open access · greenAbstract readCase Reports
In one paragraph

Article in Explore (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Antiviral Activity and Underlying Mechanism ofMolecules (Basel, Switzerland) · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shuo-Wen HungDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan.
Yuan-Ching LiaoDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan; Graduate Institute of Chinese Medicine, School of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, North District, Taichung City 40402, Taiwan.
I-Chang ChiDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan.
Ting-Yen LinDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan.
Yu-Chuan LinDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan.
Hung-Jen LinDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan; Department of Chinese Medicine, School of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, North District, Taichung City 40402, Taiwan.
Sheng-Teng HuangDepartment of Chinese Medicine, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan; Department of Chinese Medicine, School of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, North District, Taichung City 40402, Taiwan; Cancer Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, No. 2, Yude Road, North District, Taichung City 404332, Taiwan; An-Nan Hospital, China Medical University, No. 66, Section 2, Zhanghe Road, Annan District, Tainan City 709, Taiwan. Electronic address: sheng.teng@yahoo.com.
China Medical University · TWChina Medical University Hospital · TWAn-Nan Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

caseSerious complications of severe coronavirus disease 2019 (COVID-19) include subcutaneous emphysema (SE) and pneumomediastinum, which are complicated to treat with conventional Western medicine. We report how combining Chinese herbal medicine (CHM) with Western medicine quickly resolved a patient's COVID-19-associated pulmonary complications, shortened hospital stay and improved quality of life. CLINICAL FEATURES AND OUTCOME: A 59-year-old male with a history of smoking and tumors was diagnosed with COVID-19 in May 2021. At hospitalization, his oxygen saturation (SpO

conclusionCHM combined with standard Western medicine improved pulmonary function, respiratory rate, blood oxygen saturation and shortened the hospital stay of a patient with severe COVID-19 complicated by SE and pneumomediastinum.

Indexed as

COVID-19Drugs, Chinese HerbalMediastinal EmphysemaSubcutaneous EmphysemaAftercareHumansMaleMiddle AgedPatient DischargeQuality of LifeTaiwanDrugs, Chinese HerbalChinese herbal medicineCOVID-19 Subcutaneous emphysemaPneumomediastinum

Identifiers

PMID34955379
PMCPMC8667518
OpenAlexW4200379284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.