Evidence map›Paper›PMID 34954744›Full record

ArticleJournal of addiction medicine

Barriers to Engagement in Opioid Use Disorder Treatment After Buprenorphine Induction.

Scott A Simpson, Melissa Hordes, Joshua Blum, Deborah Rinehart, Alia Al-Tayyib

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07148206 (Dronabinol and Epidiolex to Manage Uncontrolled Residual Symptoms of Buprenorphine Initiation Trial), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07148206 phase3not yet recruitingnot on this map

Dronabinol and Epidiolex to Manage Uncontrolled Residual Symptoms of Buprenorphine Initiation Trial

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2028Enrolled40ConditionsOpioid Use DisorderArmsDronabinol Capsules, Epidiolex 100 mg/mL Oral Solution, Placebo Dronabinol, Placebo Epidiolex
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Scott A SimpsonFrom the Department of Behavioral Health Services, Denver Health and Hospital Authority, Denver, CO (SAS, JB); Public Health Institute at Denver Health, Denver Health and Hospital Authority, Denver, CO (MH, AA-T); Center for Health Systems Research, Office of Research, Denver Health and Hospital Authority, Denver, CO (DR, AA-T).
Melissa Hordes
Joshua Blum
Deborah Rinehart
Alia Al-Tayyib
Health and Hospital Corporation · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Linkage navigation to enhance initiation and engagement in treatment for opioid use disorder to prevent overdose.R01CE003006 · CE · DENVER HEALTH AND HOSPITAL AUTHORITY · PI AL-TAYYIB, ALIA · 2018 to 2019
$1.5M
ACL HHS R01CE003006NCIPC CDC HHS R01 CE003006NCRR NIH HHS UL1 RR025780
6 · The paper itself

Abstract

objectivesExpanded access to buprenorphine induction, including via emergency departments, increases the likelihood of treatment engagement for patients with opioid use disorder (OUD). However, longer-term retention among these patients remains a challenge. In this study, we aimed to identify barriers to engaging and retaining patients with OUD in care and additional services that might improve retention.

methodsWe surveyed counselors at an urban safety net addictions treatment clinic.

resultsTwenty-five of 27 (93%) eligible counselors responded. Counselors described patients who were homeless, had no prior treatment history, or lacked health insurance as hardest to retain in treatment. Housing assistance, residential treatment placement, regular access to a phone, and mental health services were thought to be most beneficial for improving retention. Respondents most often reported that screening for services should happen at intake, and almost all respondents agreed that "retention of patients receiving treatment for OUD would improve with a dedicated case manager and/or more coordinated case management services."

conclusionsEngagement in OUD treatment would be improved with interventions to mitigate the significant social and psychiatric comorbidities of addiction. Community- and emergency department-initiated buprenorphine is a promising intervention whose full promise cannot be realized without interventions to improve treatment retention.

Indexed as

BuprenorphineIll-Housed PersonsOpioid-Related DisordersComorbidityEmergency Service, HospitalHumansOpiate Substitution TreatmentBuprenorphine

Identifiers

PMID34954744
PMCPMC9549700
OpenAlexW4200164299

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.