SynthesisJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2022
Associations Between Stroke Localization and Delirium: A Systematic Review and Meta-Analysis.
Synthesis in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Prevention and Treatment of ICU Delirium in Brain Injured Patients.Current neurology and neuroscience reports · 2026Review
- Cognitive Recovery After Poststroke Delirium (RECOVER): Protocol for a Longitudinal Multimodal Study on Cognitive Assessment in Patients With Stroke.JMIR research protocols · 2026Article
- Quetiapine Use Is Associated with Longer ICU Stay Compared to Control and Haloperidol: A Propensity Score-Matched Analysis Using the MIMIC-IV Database.Journal of clinical medicine · 2025Article
- Occurrence Rates of Delirium in Brain Tumor Patients: A Systematic Review and Meta-Analysis.Cancers · 2025Review
- Neuroimaging Markers of Brain Reserve and Associations with Delirium in Patients with Intracerebral Hemorrhage.Neurocritical care · 2025Article
- Establishment and validation of a nomogram of postoperative delirium in patients undergoing cardiac surgery: a retrospective study of MIMIC-IV.BMC cardiovascular disorders · 2025Article
- Delirium following mechanical thrombectomy for ischemic stroke - individuals at risk, imaging biomarkers and prognosis.Frontiers in aging neuroscience · 2025Article
- Current perspectives on the early identification and management of delirium after acute stroke reperfusion therapy.Frontiers in neurology · 2025Review
- Validating the Fluctuating Mental Status Evaluation in Neurocritically Ill Patients With Acute Stroke.Critical care medicine · 2024Article
- Investigating delirium in stroke with an EEG lens: Focal lesions with global impact?Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Article
- Integrative Approaches in Acute Ischemic Stroke: From Symptom Recognition to Future Innovations.Biomedicines · 2023Review
- Associations between early in-hospital medications and the development of delirium in patients with stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023Article
- Review
- Effects of Melatonin Administration on Post-Stroke Delirium in Patients with Intracerebral Hemorrhage.Journal of clinical medicine · 2023Article
- The Role of Vascular Risk Factors in Post-Stroke Delirium: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Risk Factors for Delirium Superimposed on Dementia in Elderly Patients in Comprehensive Ward.American journal of Alzheimer's disease and other dementiasArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesDelirium is common among patients with acute stroke and associated with worse outcomes. However, it is unclear which stroke locations or types are most associated with delirium. MATERIALS AND
methodsWe systematically reviewed studies of patients with acute stroke that reported stroke locations and types by delirium status. We included papers in any language, through a combined search from January 2010 to June 2021. Case studies with less than 20 patients, case-control studies, and randomized controlled trials were excluded. MEDLINE, EMBASE, PsycINFO, CINAHL, and Alois databases were searched. Pooled relative risks were calculated using bivariate random effects models or network meta-analysis. Methodological quality was assessed across 8 factors.
results31 patient samples representing 8329 patients were included. Delirium was more common in patients with supratentorial lesions than infratentorial (RR [Relative Risk] 2.01, CI [Confidence Interval] 1.49-2.72); anterior circulation lesions than posterior (RR 1.41, CI 1.13-1.78); and cortical lesions than subcortical (RR 1.54, CI 1.25-1.89). Stroke side was not associated with delirium (right vs. left: RR 0.99, CI 0.77-1.28). Delirium was more common in patients with hemorrhagic strokes than ischemic (RR 1.74, CI 1.42-2.11) and patients with preexisting qualitative atrophy (RR 1.66, CI 1.21-2.27).
conclusionSeveral brain localizations and types of strokes were associated with delirium. Conclusions were in part limited by the heterogeneity of studies and broad or qualitative lesion descriptions. These results may assist in anticipating the risk of delirium in acute stroke and highlight brain networks and pathologies that may be involved in the pathophysiology of delirium.
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