Evidence map›Paper›PMID 34954017›Full record

ArticleThe Journal of steroid biochemistry and molecular biology2022

Validation of the 24,25-dihydroxyvitamin D

Simon Hsu, Leila R Zelnick, Yvonne S Lin, Cora M Best, Bryan R Kestenbaum, Kenneth E Thummel, Andrew N Hoofnagle, Ian H de Boer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of steroid biochemistry and molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. The role of nutritional vitamin D in chronic kidney disease-mineral and bone disorder in children and adults with chronic kidney disease, on dialysis, and after kidney transplantation-a European consensus statement.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  2. Review
  3. Article
  4. Determination of 24,25-dihydroxyvitamin DThe Journal of steroid biochemistry and molecular biology · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Simon HsuDivision of Nephrology, Department of Medicine, University of Washington, Seattle, WA, United States; Kidney Research Institute, University of Washington, Seattle, WA, United States. Electronic address: sihsu@uw.edu.
Leila R ZelnickDivision of Nephrology, Department of Medicine, University of Washington, Seattle, WA, United States; Kidney Research Institute, University of Washington, Seattle, WA, United States.
Yvonne S LinDepartment of Pharmaceutics, University of Washington, Seattle, WA, United States.
Cora M BestKidney Research Institute, University of Washington, Seattle, WA, United States; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Bryan R KestenbaumDivision of Nephrology, Department of Medicine, University of Washington, Seattle, WA, United States; Kidney Research Institute, University of Washington, Seattle, WA, United States; Department of Epidemiology, University of Washington, Seattle, WA, United States.
Kenneth E ThummelDepartment of Pharmaceutics, University of Washington, Seattle, WA, United States.
Andrew N HoofnagleKidney Research Institute, University of Washington, Seattle, WA, United States; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, United States.
Ian H de BoerDivision of Nephrology, Department of Medicine, University of Washington, Seattle, WA, United States; Kidney Research Institute, University of Washington, Seattle, WA, United States; Puget Sound VA Healthcare System, Seattle, WA, United States.
University of Washington · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 1986 to 2026
$30.4M
Nutrition, Obesity and Atherosclerosis Training ProgramT32HL007028 · NHLBI · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1985 to 2026
$6.4M
Hormonal Regulation of Human CYP3AR01GM063666 · NIGMS · UNIVERSITY OF WASHINGTON · PI THUMMEL, KENNETH E. · 2002 to 2017
$5.3M
RESEARCH TRAINING IN RENAL DISEASET32DK007467 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA, KESTENBAUM, BRYAN R · 1986 to 2023
$5.1M
Vitamin D Catabolism in Chronic Kidney DiseaseR01DK099199 · NIDDK · UNIVERSITY OF WASHINGTON · PI DE BOER, IAN H · 2014 to 2018
$3.2M
Comparative Safety and Efficacy of Low-dose Vitamin D in Kidney FailureK23DK136930 · NIDDK · UNIVERSITY OF WASHINGTON · PI Simon Hsu · 2023 to 2026
$747k
F32 Childcare Costs Supplement: Assessment of the Vitamin D Metabolite Ratio as a Therapeutic Target in Clinical PracticeF32DK128986 · NIDDK · UNIVERSITY OF WASHINGTON · PI HSU, SIMON · 2021 to 2022
$93k
NCATS NIH HHS UL1 TR002319NHLBI NIH HHS T32 HL007028NIDDK NIH HHS F32 DK128986NIDDK NIH HHS K23 DK136930NIDDK NIH HHS P30 DK035816NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R01 DK099199NIDDK NIH HHS T32 DK007467NIGMS NIH HHS R01 GM063666
6 · The paper itself

Abstract

The formation of 24,25-dihydroxyvitamin D (24,25(OH)

Indexed as

CalcifediolRenal Insufficiency, Chronic24,25-Dihydroxyvitamin D 3AgedBiomarkersFemaleHumansMaleMiddle AgedVitamin DVitamins24,25-dihydroxyvitamin D24,25-Dihydroxyvitamin D 325-hydroxyvitamin DBiomarkersCalcifediolVitamin DVitaminsMineral metabolismVitamin DVitamin D metabolite ratio

Identifiers

PMID34954017
PMCPMC8837693
OpenAlexW4200537514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.