Evidence map›Paper›PMID 34953893›Full record

ReviewLife sciences2022

The effect of emerging tobacco related products and their toxic constituents on thrombosis.

Ahmed B Alarabi, Patricia A Lozano, Fadi T Khasawneh, Fatima Z Alshbool

Open access · greenAbstract readReview
In one paragraph

Review in Life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Unravelling the Therapeutic Potential of Cysteine for Cardiovascular Health.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Observational
  11. Review
  12. Review
  13. Article
  14. Electronic Cigarette Harms: Aggregate Evidence Shows Damage to Biological Systems.International journal of environmental research and public health · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Ten things to know about ten cardiovascular disease risk factors - 2022.American journal of preventive cardiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ahmed B AlarabiDepartment of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy Texas A&M University, Kingsville, TX, USA.
Patricia A LozanoDepartment of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy Texas A&M University, Kingsville, TX, USA.
Fadi T KhasawnehDepartment of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy Texas A&M University, Kingsville, TX, USA. Electronic address: fkhasawneh@tamu.edu.
Fatima Z AlshboolDepartment of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy Texas A&M University, Kingsville, TX, USA. Electronic address: falshbool@tamu.edu.
Texas A&M University – Kingsville · US

Funding

The Mechanistic Impact of Paternal Electronic Nicotine Delivery Systems Exposure on ThrombogenesisR01HL145053 · NHLBI · UNIVERSITY OF TEXAS EL PASO · PI Fadi T Khasawneh · 2019 to 2026
$3.6M
Investigation of Platelet G-Protein Coupled ReceptorsR15HL115567 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI KHASAWNEH, FADI T · 2013 to 2016
$838k
In Utero Third-Hand Smoke Impact on Platelet Function and ThrombogenesisR21ES029345 · NIEHS · UNIVERSITY OF TEXAS EL PASO · PI KHASAWNEH, FADI T · 2018 to 2020
$416k
The Impact of Third-Hand E#Cigarette Exposure on Platelet Function and ThrombogenesisR03ES030486 · NIEHS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALSHBOOL, FATIMA Z. · 2020 to 2021
$152k
NHLBI NIH HHS R01 HL145053NHLBI NIH HHS R15 HL115567NIEHS NIH HHS R03 ES030486NIEHS NIH HHS R21 ES029345
6 · The paper itself

Abstract

Although conventional cigarette smoking is declining, emerging tobacco related products (ETRPs) are currently gaining ground, especially among the youth. These products include electronic cigarettes, waterpipes/hookah, cigars/cigarillo, smokeless tobacco, and heat-not-burn cigarettes. The observed increase in the use of ETRPs is multifactorial and complex but appears to be mainly driven by efforts from the major tobacco companies to reinvent themselves, and present more appealing and allegedly safe(r) tobacco products. However, it is becoming apparent that these products produce substantial amounts of toxic chemicals, many of which have been shown to exert negative health effects, including in the context of the cardiovascular system. Thus, there has been research efforts, albeit limited in general, to characterize the health impact of these products on occlusive/thrombotic cardiovascular diseases (CVD). In this review, we will discuss the potential impact of ETRPs on thrombosis-based CVD. Specifically, we will review how these products and the major chemicals they produce and/or emit can trigger key players in the process of thrombosis, namely inflammation, oxidative stress, platelets, coagulation, and the vascular endothelium, and the relationship between these effects.

Indexed as

Cigarette SmokingElectronic Nicotine Delivery SystemsHumansSmoking Water PipesThrombosisTobacco ProductsTobacco, SmokelessTobacco UseCigars/cigarillose-CigaretteEmerging tobacco related productsHeat-not-burn tobaccoSmokeless tobaccoWaterpipe/hookah

Identifiers

PMID34953893
PMCPMC9118784
OpenAlexW4200606644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.