Evidence map›Paper›PMID 34953784›Full record

ArticleJournal of the American Medical Directors Association2022

Advancing Clinical Trials in Nursing Homes: A Proposed Roadmap to Success.

Jerry H Gurwitz, Charlene C Quinn, Ivan H Abi-Elias, Alyce S Adams, Rosie Bartel, Alice Bonner, Rebecca Boxer, Christopher Delude, David Gifford, Bruce Hanson and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Medical Directors Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jerry H GurwitzMeyers Health Care Institute, Worcester, MA, USA; UMass Chan Medical School, Worcester, MA, USA. Electronic address: Jerry.Gurwitz@umassmed.edu.
Charlene C QuinnUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Ivan H Abi-EliasMeyers Health Care Institute, Worcester, MA, USA.
Alyce S AdamsStanford University School of Medicine, Stanford, CA, USA.
Rosie BartelAGING Patient/Caregiver Advisory Council, Worcester, MA, USA.
Alice BonnerInstitute for Healthcare Improvement, Boston, MA, USA; Johns Hopkins University School of Nursing, Baltimore, MD, USA.
Rebecca BoxerKaiser Permanente Colorado, Denver, CO, USA.
Christopher DeludeMeyers Health Care Institute, Worcester, MA, USA.
David GiffordAmerican Health Care Association, Washington, DC, USA.
Bruce HansonAGING Patient/Caregiver Advisory Council, Worcester, MA, USA.
Kouta ItoMeyers Health Care Institute, Worcester, MA, USA; UMass Chan Medical School, Worcester, MA, USA.
Paavani JainUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Jay S MagazinerUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Kathleen M MazorMeyers Health Care Institute, Worcester, MA, USA; UMass Chan Medical School, Worcester, MA, USA.
Susan L MitchellHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research, Boston, MA, USA.
Lona ModyUniversity of Michigan, Ann Arbor, MI, USA.
David NaceUniversity of Pittsburgh, Pittsburgh, PA, USA.
Joseph OuslanderFlorida Atlantic University, Boca Raton, FL, USA.
JoAnne ReifsnyderGenesis Healthcare, Kenneth Square, PA, USA.
Barbara ResnickUniversity of Maryland School of Nursing, Baltimore, MD, USA.
Sheryl ZimmermanUNC Chapel Hill, Chapel Hill, NC, USA.

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Preparing For What Is Next With Aducanumab In Real World SettingsR33AG057806 · NIA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Christopher Barrett Bowling, Ana Roman Quinones · 2018 to 2026
$9.0M
NIA NIH HHS P30 AG024824NIA NIH HHS R33 AG057806NIDDK NIH HHS P30 DK092924
6 · The paper itself

Abstract

An effective clinical research effort in nursing homes to address prevention and treatment of COVID-19 faced overwhelming challenges. Under the Health Care Systems Research Network-Older Americans Independence Centers AGING Initiative, a multidisciplinary Stakeholder Advisory Panel was convened to develop recommendations to improve the capability of the clinical research enterprise in US nursing homes. The Panel considered the nursing home as a setting for clinical trials, reviewed the current state of clinical trials in nursing homes, and ultimately developed recommendations for the establishment of a nursing home clinical trials research network that would be centrally supported and administered. This report summarizes the Panel's recommendations, which were developed in alignment with the following core principles: build on available research infrastructure where appropriate; leverage existing productive partnerships of researchers with groups of nursing homes and nursing home corporations; encompass both efficacy and effectiveness clinical trials; be responsive to a broad range of stakeholders including nursing home residents and their care partners; be relevant to an expansive range of clinical and health care delivery research questions; be able to pivot as necessary to changing research priorities and circumstances; create a pathway for industry-sponsored research as appropriate; invest in strategies to increase diversity in study populations and the research workforce; and foster the development of the next generation of nursing home researchers.

Indexed as

COVID-19AgedDelivery of Health CareHumansNursing HomesSARS-CoV-2United Statesclinical trialsCOVID-19long-term careNursing homespandemic

Identifiers

PMID34953784
PMCPMC8692165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.