Evidence map›Paper›PMID 34953433›Full record

Trial reportAddictive behaviors2022

Effects of arousal modulation via resonance breathing on craving and affect in women with substance use disorder.

Julianne L Price, Marsha E Bates, Julie Morgano, Sabrina Todaro, Sarah Grace Uhouse, Evgeny Vaschillo, Bronya Vaschillo, Anthony Pawlak, Jennifer F Buckman

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addictive behaviors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05830773 (Resonance Breathing Opioid Use Disorder), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05830773 nacompletednot on this map

Resonance Breathing Opioid Use Disorder

TypeinterventionalSponsorUniversity of Texas at AustinRan2021 to 2023Enrolled60ConditionsSubstance-Related DisordersArmsResonance Breathing Exercises
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Effects of behavioral interventions on stress reactivity in adults with substance use disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heart Rate Variability Biofeedback for Substance Use Disorder: Health Policy Implications.Policy insights from the behavioral and brain sciences · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Julianne L PriceCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States; Department of Kinesiology and Health, Rutgers University-New Brunswick, 70 Lipman Drive, New Brunswick, NJ 08901, United States.
Marsha E BatesCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States; Department of Kinesiology and Health, Rutgers University-New Brunswick, 70 Lipman Drive, New Brunswick, NJ 08901, United States.
Julie MorganoCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States.
Sabrina TodaroCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States; Department of Psychology, Rutgers University-New Brunswick, 152 Frelinghuysen, Piscataway, NJ 08854, United States; Department of Psychology, Rutgers University-Camden, 311 N. Fifth St., Camden, NJ 08102, United States.
Sarah Grace UhouseCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States; Department of Psychology, Rutgers University-New Brunswick, 152 Frelinghuysen, Piscataway, NJ 08854, United States; Department of Psychology, Rutgers University-Camden, 311 N. Fifth St., Camden, NJ 08102, United States.
Evgeny VaschilloCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States.
Bronya VaschilloCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States.
Anthony PawlakCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States.
Jennifer F BuckmanCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick, 607 Allison Rd., Piscataway, NJ 08854, United States; Department of Kinesiology and Health, Rutgers University-New Brunswick, 70 Lipman Drive, New Brunswick, NJ 08901, United States. Electronic address: jbuckman@smithers.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Project IMPACT: In-the-Moment Protection from Automatic Capture by TriggersR01AA023667 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BATES, MARSHA E., BUCKMAN, JENNIFER F. · 2015 to 2019
$2.7M
Molecular Neuroscience of Alcohol and Drug Abuse Research TrainingT32AA028254 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI ASTON-JONES, GARY S., SARKAR, DIPAK KUMAR · 2019 to 2023
$1.3M
Deconstructing the temporal and multi-level influences of the baroreflex mechanism on alcohol use behaviorsK02AA025123 · NIAAA · RUTGERS, THE STATE UNIV OF N.J. · PI BUCKMAN, JENNIFER F. · 2017 to 2021
$762k
NIAAA NIH HHS K02 AA025123NIAAA NIH HHS R01 AA023667NIAAA NIH HHS T32 AA028254
6 · The paper itself

Abstract

backgroundCraving for alcohol and other drugs is a complex in-the-moment experience that involves within-person changes in physiological arousal and affect. We evaluated the utility of a just-in-time, self-administered resonance breathing smartphone application (app) to reduce craving and improve affect in women during outpatient treatment for substance use disorders (SUD).

methodsWomen (N = 57) receiving outpatient addiction treatment were randomized to practice either cardiovascular resonance breathing (0.1 Hz/6 breaths per minute) or a sham (∼0.23 Hz/14 breaths per minute) in the face of urges over an 8-week intervention. Craving (Penn Alcohol Craving Scale) and affect (Positive and Negative Affect Scale) were collected weekly throughout the intervention. App data were uploaded weekly to assess frequency of use. Generalized Estimated Equations modeled craving and affect as a function of group randomization and app use frequency across the 8-week intervention.

findingsHigher levels of craving were associated with more frequent app use. The group X app use interaction was significant for craving. Frequent app use during the intervention phase was associated with lower craving levels in the resonance breathing group relative to the sham group over the 8-week intervention. There was no effect of app use frequency on affect measures.

conclusionsWomen assigned to practice sham breathing who used the intervention frequently experienced elevations in craving that are commonly reported during outpatient SUD treatment. Women assigned to resonance breathing who used the intervention frequently did not experience such increases. Resonance breathing may be protective against triggers in outpatient treatment. Physiological mechanisms are discussed.

Indexed as

Mobile ApplicationsSubstance-Related DisordersArousalCravingFemaleHumansRespirationAlcohol use disorderBaroreflexCardiovascularClinical trialHeart rate variabilityResonance breathing

Identifiers

PMID34953433
PMCPMC9069782
OpenAlexW4200278606

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.