Evidence map›Paper›PMID 34953378›Full record

ArticlePoultry science2022

Investigating the dynamics of Salmonella contamination in integrated poultry companies using a whole genome sequencing approach.

José L Medina-Santana, David Ortega-Paredes, Sofia de Janon, Elton Burnett, Maria Ishida, Brian Sauders, Mieke Stevens, Christian Vinueza-Burgos

Open access · goldAbstract read
In one paragraph

Article in Poultry science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Genomic Evidence of Multidrug-ResistantbioRxiv : the preprint server for biology · 2026
    Article
  3. Investigating the dynamics ofFrontiers in veterinary science · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A PMAxxVeterinary sciences · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

José L Medina-SantanaUnidad de investigación de Enfermedades Transmitidas por Alimentos y Resistencia a los Antimicrobianos (UNIETAR), Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito 170103, Ecuador.
David Ortega-ParedesUnidad de investigación de Enfermedades Transmitidas por Alimentos y Resistencia a los Antimicrobianos (UNIETAR), Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito 170103, Ecuador.
Sofia de JanonUnidad de investigación de Enfermedades Transmitidas por Alimentos y Resistencia a los Antimicrobianos (UNIETAR), Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito 170103, Ecuador.
Elton BurnettInstitute of Parasitology, McGill University, Montreal, QC H9X3V9, Canada.
Maria IshidaDivision of Food Laboratory, New York State Department of Agriculture and Markets, Albany, NY 12206, USA.
Brian SaudersDivision of Food Laboratory, New York State Department of Agriculture and Markets, Albany, NY 12206, USA.
Mieke StevensInstitute of Tropical Medicine Antwerp, Belgium.
Christian Vinueza-BurgosUnidad de investigación de Enfermedades Transmitidas por Alimentos y Resistencia a los Antimicrobianos (UNIETAR), Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito 170103, Ecuador. Electronic address: cvinueza@uce.edu.ec.
Central University of Ecuador · ECNew York State Department of Agriculture and Markets · USInstituut voor Tropische Geneeskunde · BEMcGill University · CA

Funding

ISO/IEC Accreditation and Whole Genome Sequencing for State Testing LaboratoriesU18FD006196 · FDA · NY STATE DEPT OF AGRICULTURE/ MARKETS · PI ISHIDA, MARIA LUCIA · 2017 to 2018
$620k
Maintenance and Enhancement of ISO/IEC 17025 Accreditation and Whole Genome Sequencing for State Food Testing LaboratoriesU18FD006787 · FDA · NY STATE DEPT OF AGRICULTURE/ MARKETS · PI ISHIDA, MARIA LUCIA · 2019 to 2019
$310k
FDA HHS U18 FD006196FDA HHS U18 FD006787
6 · The paper itself

Abstract

The study of non-typhoid Salmonella in broiler integrations has been limited by the resolution of typing techniques. Although serotyping of Salmonella isolates is used as a traditional approach, it is not of enough resolution to clearly understand the dynamics of this pathogen within poultry companies. The aim of this research was to investigate the epidemiology and population dynamics of Salmonella serotypes in 2 poultry integrations using a whole genome sequencing approach. Two hundred and forty-three Salmonella isolates recovered from the broiler production chain of 2 integrated poultry companies were whole genome sequenced and analyzed with dedicated databases and bioinformatic software. The analyses of sequences revealed that S. Infantis was the most frequent serotype (82.3%). Most isolates showed a potential for resistance against medically important antibiotics and disinfectants. Furthermore, 97.5% of isolates harbored the pESI-like mega plasmid, that plays an important role in the global dissemination of AMR. SNP tree analysis showed that there were clones that are niche-specific while other ones were distributed throughout the broiler production chains. In this study, we demonstrated the potential of whole genome sequencing analysis for a comprehensive understanding of Salmonella distribution in integrated poultry companies. Data obtained with these techniques allow determination of the presence of genetic factors that play an important role in the environmental fitness and pathogenicity of Salmonella.

Indexed as

ChickensPoultryAnimalsAnti-Bacterial AgentsGenome, BacterialSalmonellaWhole Genome SequencingAnti-Bacterial Agentsantimicrobial resistancepESI-likepoultry production chainSalmonella InfantisWGS

Identifiers

PMID34953378
PMCPMC8715213
OpenAlexW3215002890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.