ArticleESC heart failure2022
Right ventricular function and its coupling to pulmonary circulation predicts exercise tolerance in systolic heart failure.
Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Right ventricular function, exercise capacity and quality of life in adults with congenital heart disease and the effect of a home-based exercise program.International journal of cardiology. Congenital heart disease · 2026Article
- Exercise testing for evaluating right ventricular (RV) function in pulmonary hypertension - A review.Lung India : official organ of Indian Chest Society · 2026Article
- Relationship between right heart catheterization and exercise testing in heart failure patients with and without pulmonary hypertension - cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- Prognostic Value of Body Weight-Independent Tricuspid Annular Plane Systolic Excursion to Systolic Pulmonary Arterial Pressure Ratio in Canine Precapillary Pulmonary Hypertension: A Retrospective Study.Animals : an open access journal from MDPI · 2025Article
- Clinical Usefulness of Right Ventricular-Pulmonary Artery Coupling in Patients with Heart Failure.Diagnostics (Basel, Switzerland) · 2025Review
- Exercise Right Ventricular-Pulmonary Arterial Coupling and Functional Outcome in Patients Undergoing Surgery for Secondary Ischemic Mitral Regurgitation.Journal of the American Heart Association · 2025Article
- Prognostic value of non-invasive right ventricle-pulmonary artery coupling in patients with pulmonary hypertension associated with left heart disease.Journal of cardiothoracic surgery · 2025Article
- Machine-Learning-Based Prediction of Exercise Intolerance of Patients With Heart Failure Using Pragmatic Submaximal Exercise Parameters.Circulation reports · 2025Article
- Association between the TAPSE/PASP ratio and exercise capacity in heart transplant candidates with advanced heart failure.Frontiers in cardiovascular medicine · 2025Article
- Right ventricular myocardial performance index as an early marker of cardiac dysfunction in systemic sclerosis.Frontiers in medicine · 2025Article
- Echocardiographic assessment for cardiopulmonary function in patients with congenital heart disease-related pulmonary arterial hypertension.BMC pulmonary medicine · 2024Article
- Application of an echocardiographic index to characterize right ventricular-pulmonary arterial coupling in heart failure.ESC heart failure · 2024Review
- Relationship of TAPSE Normalized by Right Ventricular Area With Pulmonary Compliance, Exercise Capacity, and Clinical Outcomes.Circulation. Heart failure · 2024Article
- The Prognostic Value of Right Ventricular Function in Patients with Chronic Heart Failure-A Prospective Study.Journal of clinical medicine · 2024Article
- Clinical Usefulness of Right Ventricle-Pulmonary Artery Coupling in Cardiovascular Disease.Journal of clinical medicine · 2023Review
- Estimated plasma volume status: association with congestion, cardiorenal syndrome and prognosis in precapillary pulmonary hypertension.Frontiers in cardiovascular medicine · 2023Article
- Right Ventricular Function and Exercise Tolerance in Patients with ST-Elevation Myocardial Infarction.Arquivos brasileiros de cardiologia · 2023Article
- Impact of right ventricular-pulmonary arterial coupling on clinical outcomes of tricuspid regurgitation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
- Association between Right Ventricular Function and Exercise Capacity in Patients with Chronic Heart Failure.Journal of clinical medicine · 2022Article
- Right ventricular function and its coupling to pulmonary circulation predicts exercise tolerance in systolic heart failure.ESC heart failure · 2022Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
aimsRight ventricular (RV) dysfunction, pulmonary hypertension, and exercise intolerance have prognostic values, but their interrelation is not fully understood. We investigated how RV function alone and its coupling with pulmonary circulation (RV-PA) predict cardio-respiratory fitness in patients with heart failure and reduced ejection fraction (HFrEF). METHODS AND
resultsThe Evaluation of Resynchronization Therapy for Heart Failure (EARTH) study included 205 HFrEF patients with narrow (n = 85) and prolonged (n = 120) QRS duration undergoing implantable cardioverter defibrillator implantation. All patients underwent a comprehensive evaluation with exercise tolerance tests and echocardiography. We investigated the correlations at baseline between RV parameters {size, function [tricuspid annular plane systolic excursion (TAPSE), RV fractional area change (RV-FAC), and RV myocardial performance index (RV-MPI)], pulmonary artery systolic pressure (PASP), and tricuspid regurgitation}; left ventricular ejection fraction (LVEF), left ventricular end-diastolic volume index (LVEDVi), and left atrial volume index (LAVi); and cardiopulmonary exercise test (CPET) [peak VO
conclusionsRight ventricular function assessed by echocardiography (RV-MPI and RV-FAC) is closely associated with exercise tolerance in patients with HFrEF. When the TAPSE/PASP ratio is available, this marker of RV-PA coupling becomes the stronger echocardiographic predictor of exercise capacity in this population, highlighting its potential role as a screening tool to identify patients with reduced exercise capacity and potentially triage them to formal peak VO
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.