Evidence map›Paper›PMID 34953059›Full record

ArticleCancer medicine2022

Assessing fatigue in childhood cancer survivors: Psychometric properties of the Checklist Individual Strength and the Short Fatigue Questionnaire--a DCCSS LATER study.

Adriaan Penson, Iris Walraven, Ewald Bronkhorst, Martha A Grootenhuis, Wim J E Tissing, Helena J H van der Pal, Andrica C H de Vries, Marry M van den Heuvel-Eibrink, Sebastian Neggers, Birgitta A B Versluys and 8 more

Abstract read
In one paragraph

Article in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. [A systematic review of childhood cancer-related fatigue assessment tools based on the COSMIN guidelines].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Pooled it
  2. Article
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  7. Prevalence and associations of fatigue in childhood atopic dermatitis: A cross-sectional study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Adriaan PensonDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID 0000-0001-7558-1637
Iris WalravenDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Ewald BronkhorstDepartment of Dentistry, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Martha A GrootenhuisDepartment of Psychology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Wim J E TissingPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Helena J H van der PalPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Andrica C H de VriesDepartment of Pediatric Oncology, Erasmus Medical Center, Rotterdam, The Netherlands.
Marry M van den Heuvel-EibrinkPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Sebastian NeggersPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Birgitta A B VersluysPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Marloes LouwerensDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Saskia M F PluijmPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Nicole BlijlevensDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.
Margriet van der Heiden-van der LooPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Leontien C M KremerPrincess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.
Eline van Dulmen-den BroederDepartment of Pediatric Oncology/Hematology, Amsterdam University Medical Center, Amsterdam, The Netherlands.
Hans KnoopDepartment of Medical Psychology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam Public health research institute, Amsterdam, Netherlands.
Jacqueline LoonenDepartment of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFatigue is often reported by patients with childhood cancer both during and after cancer treatment. Several instruments to measure fatigue exist, although none are specifically validated for use in childhood cancer survivors (CCS). The aim of the current study was to present norm values and psychometric properties of the Checklist Individual Strength (CIS) and Short Fatigue Questionnaire (SFQ) in a nationwide cohort of CCS.

methodsIn total, 2073 participants were included from the Dutch Childhood Cancer Survivor Study (DCCSS) LATER cohort. Normative data, construct validity, structural validity, and internal consistency were calculated for the CIS and SFQ. In addition, reliability and a cutoff score to indicate severe fatigue were determined for the SFQ.

resultsCorrelations between CIS/SFQ and vitality measures asking about fatigue were high (>0.8). Correlations between CIS/SFQ and measures of different constructs (sleep, depressive emotions, and role functioning emotional) were moderate (0.4-0.6). Confirmatory factor analysis resulted in a four-factor solution for the CIS and a one-factor solution for the SFQ with Cronbach's alpha for each (sub)scale showing good to excellent values (>0.8). Test-retest reliability of the SFQ was adequate (Pearson's correlation = 0.88; ICC = 0.946; weighted Cohen's kappa item scores ranged 0.31-0.50) and a cut-off score of 18 showed good sensitivity and specificity scores (92.6% and 91.3%, respectively).

conclusionThe current study shows that the SFQ is a good instrument to screen for severe fatigue in CCS. The CIS can be used as a tool to assess the multiple fatigue dimensions in CCS.

Indexed as

Cancer SurvivorsNeoplasmsChecklistChildFatigueHumansPsychometricsQuality of LifeReproducibility of ResultsSurveys and Questionnaireschecklist individual strengthchildhood cancer survivorspsychometric propertiessevere fatigueshort fatigue questionnaire

Identifiers

PMID34953059
PMCPMC8855897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.