Evidence map›Paper›PMID 34952957›Full record

SynthesisArchives of microbiology2021

Nanoparticle-modified PMMA to prevent denture stomatitis: a systematic review.

Amanda Aparecida Maia Neves Garcia, Carolina Yoshi Campos Sugio, Lucas José de Azevedo-Silva, Anna Clara Gurgel Gomes, André Ulisses Dantas Batista, Vinicius Carvalho Porto, Simone Soares, Karin Hermana Neppelenbroek

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Archives of microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Amanda Aparecida Maia Neves GarciaDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.
Carolina Yoshi Campos SugioDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.ORCID http://orcid.org/0000-0001-8934-4472
Lucas José de Azevedo-SilvaDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.ORCID http://orcid.org/0000-0002-6636-8022
Anna Clara Gurgel GomesDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.ORCID http://orcid.org/0000-0002-9990-3589
André Ulisses Dantas BatistaDepartment of Restorative Dentistry, Federal University of Paraíba, João Pessoa, PB, Brazil.ORCID http://orcid.org/0000-0003-1593-0174
Vinicius Carvalho PortoDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.ORCID http://orcid.org/0000-0002-6609-9934
Simone SoaresDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil.ORCID http://orcid.org/0000-0003-0811-7302
Karin Hermana NeppelenbroekDepartment of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo (USP), Al. Octávio Pinheiro Brisola, 9-75, Bauru, SP, 17012-901, Brazil. khnepp@yahoo.com.br.ORCID http://orcid.org/0000-0001-7086-2667
Universidade de São Paulo · BRUniversidade Federal da Paraíba · BR

Funding

conselho nacional de desenvolvimento científico e tecnológico 133425/2020-7coordenação de aperfeiçoamento de pessoal de nível superior Finance Code 001
6 · The paper itself

Abstract

This systematic review aimed to evaluate the antifungal effectiveness of polymethylmetacrylate (PMMA) modified by nanoparticles (NPs) and to compare it with conventional acrylic resins for denture bases. The present study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Searches were performed using PubMed, SCOPUS, SciELO, EMBASE, and LILACS. Eligibility criteria were as recommended by PRISMA. The studies presented great variability regarding NP type, synthesis method, antifungal evaluation method, and antifungal effect. The most commonly used NPs were silver (AgNP) and zinc oxide (ZnONP), ranging in size from 10 to 100 nm. The incorporation methods were mechanical or agitated. Despite PMMA modification by ZnONP being shown in vitro to be a combination with the best antifungal effect, future studies are still needed to determine the minimum inhibitory concentration for Candida spp. and assess its biocompatibility before the protocol is clinically tested.

Indexed as

NanoparticlesStomatitis, DentureCandida albicansDenture BasesHumansPolymethyl MethacrylatePolymethyl MethacrylateBiofilmsCandida albicansDenture BasesNanoparticlesPMMA

Identifiers

PMID34952957
OpenAlexW4200062129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.