ReviewTrends in neurosciences2022
Ocular and extraocular roles of neuropsin in vertebrates.
Review in Trends in neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Bioinformatic Analysis and Tissue-Specific Expression of Clock Genes andAnimals : an open access journal from MDPI · 2026Article
- Beyond SWS1 Cones: Canonical and Noncanonical Routes of Ultraviolet Sensitivity in the Avian Retina.Birds (Basel, Switzerland) · 2026Article
- Minimal Mimics and Maps of Natural Light for Mammals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Wavelength-dependent sleep state manipulation using light pulses in Pogona vitticeps.Communications biology · 2026Article
- Neuropsin-expressing cells in the retina affect melanopsin expression and response to light in mice.Scientific reports · 2026Article
- The physiological functions of OPN5m.Eye and vision (London, England) · 2025Review
- Opsin expression varies across larval development and taxa in pteriomorphian bivalves.Frontiers in neuroscience · 2024Article
- All Light, Everywhere? Photoreceptors at Nonconventional Sites.Physiology (Bethesda, Md.) · 2024Review
- Convergent evolution of animal and microbial rhodopsins.RSC advances · 2023Review
- Cell-type expression and activation by light of neuropsins in the developing and matureFrontiers in cellular neuroscience · 2023Article
- Multiple Factors Causing Myopia and the Possible Treatments: A Mini Review.Frontiers in public health · 2022Review
- Rhodopsins: An Excitingly Versatile Protein Species for Research, Development and Creative Engineering.Frontiers in chemistry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The ability to detect and adapt to different levels of ambient light is critical for animal survival. Light detection is the basis of vision, but light also regulates eye development and drives several non-image-forming functions, including synchronizing circadian rhythms to the daily light/dark cycle, restricting pupils in response to changes in light intensity, and modulating mood in response to light. Until the early 2000s, these functions were thought to be solely mediated by ocular photoreceptors. However, neuropsin (OPN5), a UV-sensitive opsin, has been receiving growing attention, as new methods have revealed previously unappreciated functions of OPN5. In fact, OPN5-mediated extraocular and deep-brain photoreception have recently been described for the first time in mammals. This review aims to synthesize current knowledge of the properties and functions of OPN5 across vertebrates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.