ArticleNeurorehabilitation and neural repair2022
Corticospinal Tract Lesion Load Originating From Both Ventral Premotor and Primary Motor Cortices Are Associated With Post-stroke Motor Severity.
Article in Neurorehabilitation and neural repair, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Self-Organizing Recruitment of Compensatory Cortical Areas Post-Stroke Can Maximize Residual Motor Performance.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Toward Precision Post-Stroke Rehabilitation Medicine: Integrating Molecular, Imaging, and Computational Biomarkers for Functional Outcome Prediction.Journal of clinical medicine · 2025Review
- Neuroengineering approaches assessing structural and functional changes of motor descending pathways in stroke.Progress in biomedical engineering (Bristol, England) · 2025Review
- Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke.Stroke · 2025Article
- Article
- Heteronymous feedback from quadriceps onto soleus in stroke survivors.Journal of neuroengineering and rehabilitation · 2025Article
- Excitation-inhibition imbalance in the motor control network: a key factor in post-stroke spasticity.Frontiers in human neuroscience · 2025Review
- Early corticospinal tract sub-pathway lesion load and integrity predict post-stroke motor outcomes.Frontiers in human neuroscience · 2025Article
- Corticospinal premotor fibers facilitate complex motor control after stroke.Annals of clinical and translational neurology · 2024Article
- Heteronymous feedback from quadriceps onto soleus in stroke survivors.Research square · 2024Article
- Data-driven biomarkers better associate with stroke motor outcomes than theory-based biomarkers.Brain communications · 2024Article
- Outcome Prediction by Combining Corticospinal Tract Lesion Load with Diffusion-tensor Fractional Anisotropy in Patients after Hemorrhagic Stroke.Progress in rehabilitation medicine · 2024Article
- Normative connectome-based analysis of sensorimotor deficits in acute subcortical stroke.Frontiers in neuroscience · 2024Article
- Association between activity in the ventral premotor cortex and spinal cord activation during force generation-A combined cortico-spinal fMRI study.Human brain mapping · 2023Article
- Post-Stroke Brain Health Monitoring and Optimization: A Narrative Review.Journal of clinical medicine · 2023Review
- Data-driven biomarkers outperform theory-based biomarkers in predicting stroke motor outcomes.bioRxiv : the preprint server for biology · 2023Article
- Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke.Neurology · 2023Observational
- The elusive metric of lesion load.Brain structure & function · 2023Review
- Pathway-Specific Mediation Effect Between Structure, Function, and Motor Impairment After Subcortical Stroke.Neurology · 2023Article
- Modulation of neural co-firing to enhance network transmission and improve motor function after stroke.Neuron · 2022Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Lesion load of the corticospinal tract (CST-LL), a measure of overlap between a stroke lesion and the CST, is one of the strongest predictors of motor outcomes following stroke. CST-LL is typically calculated by using a probabilistic map of the CST originating from the primary motor cortex (M1). However, higher order motor areas also have projections that contribute to the CST and motor control. In this retrospective study, we examined whether evaluating CST-LL from additional motor origins is more strongly associated with post-stroke motor severity than using CST-LL originating from M1 only. We found that lesion load to both the ventral premotor (PMv) cortex and M1 were more strongly related to stroke motor severity indexed by Fugl-Meyer Assessment cut-off scores than CST-LL of M1 alone, suggesting that higher order motor regions add clinical relevance to motor impairment.
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