Evidence map›Paper›PMID 34951591›Full record

ArticleeLife2021

De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for

Thomas Laval, Laura Pedró-Cos, Wladimir Malaga, Laure Guenin-Macé, Alexandre Pawlik, Véronique Mayau, Hanane Yahia-Cherbal, Océane Delos, Wafa Frigui, Justine Bertrand-Michel and 2 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Mce transport systems inJournal of bacteriology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Thomas LavalImmunobiology of Infection Unit, Institut Pasteur, INSERM U1224, Université de Paris, Paris, France.ORCID 0000-0002-9359-2783
Laura Pedró-CosImmunobiology of Infection Unit, Institut Pasteur, INSERM U1224, Université de Paris, Paris, France.
Wladimir MalagaInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS-UPS UMR 5089, Toulouse, France.
Laure Guenin-MacéImmunobiology of Infection Unit, Institut Pasteur, INSERM U1224, Université de Paris, Paris, France.
Alexandre PawlikIntegrated Mycobacterial Pathogenomics Unit, Institut Pasteur, CNRS UMR 3525, Université de Paris, Paris, France.ORCID 0000-0002-5680-576X
Véronique MayauImmunobiology of Infection Unit, Institut Pasteur, INSERM U1224, Université de Paris, Paris, France.
Hanane Yahia-CherbalUniversité de Paris, Sorbonne Paris Cité, Paris, France.
Océane DelosMetaboHUB-MetaToul, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France.
Wafa FriguiIntegrated Mycobacterial Pathogenomics Unit, Institut Pasteur, CNRS UMR 3525, Université de Paris, Paris, France.
Justine Bertrand-MichelMetaboHUB-MetaToul, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France.
Christophe GuilhotInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS-UPS UMR 5089, Toulouse, France.
Caroline DemangelImmunobiology of Infection Unit, Institut Pasteur, INSERM U1224, Université de Paris, Paris, France.ORCID 0000-0001-7848-586X
Inserm · FRCentre National de la Recherche Scientifique · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Successful control of

Indexed as

AnimalsCell LineFatty Acids, UnsaturatedFemaleHumansImmunity, InnateImmunologic FactorsMaleMiceMycobacterium tuberculosisNutrientsFatty Acids, UnsaturatedImmunologic FactorsNutrientsfatty acidsimmunologyimmunomodulationinfectious diseaseinflammationinnate immunitymacrophagesmicrobiologymouseMycobacterium tuberculosisnutrient

Identifiers

PMID34951591
PMCPMC8752091
OpenAlexW4226053247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.