Evidence map›Paper›PMID 34951543›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2022

Assessing hemodynamics from the photoplethysmogram to gain insights into vascular age: a review from VascAgeNet.

Peter H Charlton, Birutė Paliakaitė, Kristjan Pilt, Martin Bachler, Serena Zanelli, Dániel Kulin, John Allen, Magid Hallab, Elisabetta Bianchini, Christopher C Mayer and 6 more

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Causal graph neural networks for healthcare.Nature biomedical engineering · 2026
    Review
  7. Article
  8. Wearable Flexible Sensors for Cardiovascular Disease Monitoring.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Vascular waveform analysis using Bayesian pulse deconvolution.bioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 10 countries.

Peter H CharltonDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-3836-8655
Birutė PaliakaitėBiomedical Engineering Institute, Kaunas University of Technology, Kaunas, Lithuania.ORCID 0000-0002-4831-6587
Kristjan PiltDepartment of Health Technologies, Tallinn University of Technology, Tallinn, Estonia.
Martin BachlerBiomedical Systems, Center for Health and Bioresources, AIT Austrian Institute of Technology, Seibersdorf, Austria.
Serena ZanelliLaboratoire Analyze, Géométrie et Applications, University Sorbonne Paris Nord, Paris, France.
Dániel KulinInstitute of Translational Medicine, Semmelweis University, Budapest, Hungary.
John AllenResearch Centre for Intelligent Healthcare, Coventry University, Coventry, United Kingdom.
Magid HallabAxelife, Redon, France.
Elisabetta BianchiniInstitute of Clinical Physiology, CNR, Pisa, Italy.
Christopher C MayerBiomedical Systems, Center for Health and Bioresources, AIT Austrian Institute of Technology, Seibersdorf, Austria.
Dimitrios Terentes-PrintziosHypertension and Cardiometabolic Unit, First Department of Cardiology, Hippokration Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Verena DittrichRedwave Medical, Gesellschaft mit beschränkter Haftung, Jena, Germany.
Bernhard HametnerBiomedical Systems, Center for Health and Bioresources, AIT Austrian Institute of Technology, Seibersdorf, Austria.ORCID 0000-0003-2048-1019
Dave VeerasingamDepartment of Cardiothoracic Surgery, Galway University Hospitals, Galway, Ireland.
Dejan ŽikićFaculty of Medicine, Institute of Biophysics, University of Belgrade, Belgrade, Serbia.ORCID 0000-0003-3247-9071
Vaidotas MarozasBiomedical Engineering Institute, Kaunas University of Technology, Kaunas, Lithuania.
Austrian Institute of Technology · ATCentre Hospitalier de Redon · FRKaunas University of Technology · LTIntelligent Health (United Kingdom) · GBIstituto di Fisiologia Clinica · ITNational and Kapodistrian University of Athens · GRSemmelweis University · HUTallinn University of Technology · EEUniversity Hospital Galway · IEUniversity of Belgrade · RSUniversity of London · GB

Funding

Elucidating Cellular Aging and Quality Control Pathways through Meiotic DifferentiationR01AG071801 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2021 to 2025
$1.9M
REDOX CHEMISTRY &BIOCHEMISTRY OF ORGANOSULFUR COMPOUNDSR01HL015104 · NHLBI · UNIVERSITY OF ARIZONA · PI GLASS, RICHARD S · 1985 to 1992
–
British Heart Foundation FS/20/20/34626British Heart Foundation PG/15/104/31913
6 · The paper itself

Abstract

The photoplethysmogram (PPG) signal is widely measured by clinical and consumer devices, and it is emerging as a potential tool for assessing vascular age. The shape and timing of the PPG pulse wave are both influenced by normal vascular aging, changes in arterial stiffness and blood pressure, and atherosclerosis. This review summarizes research into assessing vascular age from the PPG. Three categories of approaches are described:

Indexed as

PhotoplethysmographyVascular StiffnessBlood PressureHemodynamicsPulse Wave AnalysisReproducibility of Resultsarterial stiffnessarteriosclerosisatherosclerosisblood pressurephotoplethysmographypulse wave velocity

Identifiers

PMID34951543
PMCPMC8917928
OpenAlexW4200107443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.