Evidence map›Paper›PMID 34951428›Full record

ArticleDalton transactions (Cambridge, England : 2003)2022

2-(4-Hydroxyphenyl)benzothiazole dicarboxylate ester TACN chelators for

Yujue Wang, Truc T Huynh, Nilantha Bandara, Hong-Jun Cho, Buck E Rogers, Liviu M Mirica

Open access · greenAbstract read
In one paragraph

Article in Dalton transactions (Cambridge, England : 2003), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  8. ACS omega · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yujue WangDepartment of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, USA. mirica@illinois.edu.
Truc T HuynhDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri 63108, USA.
Nilantha BandaraDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri 63108, USA.ORCID http://orcid.org/0000-0001-5172-9828
Hong-Jun ChoDepartment of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, USA. mirica@illinois.edu.
Buck E RogersDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri 63108, USA.
Liviu M MiricaDepartment of Chemistry, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, Illinois 61801, USA. mirica@illinois.edu.ORCID http://orcid.org/0000-0003-0584-9508
University of Illinois Urbana-Champaign · USWashington University in St. Louis · US

Funding

NOVEL BIFUNCTIONAL CHEMICAL AGENTS AS THERANOSTIC TOOLS FOR AMYLOID DISEASESR01GM114588 · NIGMS · WASHINGTON UNIVERSITY · PI MIRICA, LIVIU M. · 2015 to 2019
$1.4M
NIGMS NIH HHS R01 GM114588
6 · The paper itself

Abstract

Herein we report a new series of bifunctional chelators (BFCs) with high affinity for amyloid β aggregates, strong binding affinity towards Cu(II), and favorable lipophilicity for potential blood-brain barrier (BBB) penetration. The alkyl carboxylate ester pendant arms show high binding affinity towards Cu(II). The BFCs form stable

Indexed as

Copper RadioisotopesPositron-Emission TomographyAlzheimer DiseaseAmyloidogenic ProteinsAnimalsBenzothiazolesChelating AgentsMiceMice, TransgenicMolecular StructureMutationRadiopharmaceuticalsAmyloidogenic ProteinsBenzothiazolesChelating AgentsCopper-64Copper RadioisotopesRadiopharmaceuticals

Identifiers

PMID34951428
PMCPMC8969080
OpenAlexW4200165743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.