Evidence map›Paper›PMID 34950978›Full record

ArticleTropical animal health and production2021

Diversity of the BoLA-DRB3 gene in cattle breeds from tropical and subtropical regions of Argentina.

Magalí Nicole Valenzano, María Eugenia Caffaro, Veronica Viviana Lia, Mario Poli, Silvina Elizabeth Wilkowsky

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Magalí Nicole ValenzanoInstituto de Agrobiotecnología Y Biología Molecular (IABIMO) (INTA-CONICET), de los Reseros Y Nicolás Repetto S/N, Hurlingham (B1686), Buenos Aires, Argentina.
María Eugenia CaffaroInstituto Nacional de Tecnología Agropecuaria CICVyA-CNIA, Instituto de Genética "Ewald A. Favret", de Los Reseros Y Nicolás Repetto S/N, Hurlingham (B1686), Buenos Aires, Argentina.
Veronica Viviana LiaInstituto de Agrobiotecnología Y Biología Molecular (IABIMO) (INTA-CONICET), de los Reseros Y Nicolás Repetto S/N, Hurlingham (B1686), Buenos Aires, Argentina.
Mario PoliInstituto Nacional de Tecnología Agropecuaria CICVyA-CNIA, Instituto de Genética "Ewald A. Favret", de Los Reseros Y Nicolás Repetto S/N, Hurlingham (B1686), Buenos Aires, Argentina.
Silvina Elizabeth WilkowskyInstituto de Agrobiotecnología Y Biología Molecular (IABIMO) (INTA-CONICET), de los Reseros Y Nicolás Repetto S/N, Hurlingham (B1686), Buenos Aires, Argentina. wilkowsky.silvina@inta.gob.ar.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational Agricultural Technology Institute · ARInstituto de Biotecnología y Biología Molecular · AR

Funding

FONCYT PICT 2018-2031Instituto Nacional de Tecnología Agropecuaria PE114Instituto Nacional de Tecnología Agropecuaria PE145International Atomic Energy Agency 3.10.28
6 · The paper itself

Abstract

Bovine leukocyte antigens (BoLA) have been widely studied because of their primary function in the recognition of pathogens by the immune system. To date, however, the characterization of the BoLA-DRB3 gene in Latin American Zebu and mixed zebuine breeds is scarce. By a sequence-based typing method, here we sequenced exon 2 of BoLA class II DRB3 gene in 264 animals from the five most commonly used breeds in northern Argentina (Creole, Brahman, Braford, Brangus, and Nellore).The Bos taurus, Bos indicus, and mixed breeds analyzed here contained 61 previously reported alleles. Genetic diversity was high at both allelic and nucleotide sequence levels, particularly in the mixed breeds Braford and Brangus. In contrast to previous reports on DRB3 diversity, no evidence of balancing selection was found in our data. Differentiation among breeds was highly significant, as shown by FST (F

Indexed as

CattleHistocompatibility Antigens Class IIAllelesAnimalsArgentinaBreedingGene FrequencyBoLA-DRB3 antigenHistocompatibility Antigens Class IIBoLA-DRB3Genetic diversityMixed-breedsPeptide-binding regionZebuine

Identifiers

PMID34950978
OpenAlexW4200567897

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.