Evidence map›Paper›PMID 34950934›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2019

Multiple Sclerosis Lesion Segmentation with Tiramisu and 2.5D Stacked Slices.

Huahong Zhang, Alessandra M Valcarcel, Rohit Bakshi, Renxin Chu, Francesca Bagnato, Russell T Shinohara, Kilian Hett, Ipek Oguz

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. CSAM: A 2.5D Cross-Slice Attention Module for Anisotropic Volumetric Medical Image Segmentation.IEEE Winter Conference on Applications of Computer Vision. IEEE Winter Conference on Applications of Computer Vision · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huahong ZhangVanderbilt University, Nashville, TN 37235, USA.
Alessandra M ValcarcelUniversity of Pennsylvania, Philadelphia, PA 19104, USA.
Rohit BakshiBrigham and Women's Hospital, Boston, MA 02115, USA.
Renxin ChuBrigham and Women's Hospital, Boston, MA 02115, USA.
Francesca BagnatoVanderbilt University Medical Center, Nashville, TN 37235, USA.
Russell T ShinoharaUniversity of Pennsylvania, Philadelphia, PA 19104, USA.
Kilian HettVanderbilt University, Nashville, TN 37235, USA.
Ipek OguzVanderbilt University, Nashville, TN 37235, USA.

Funding

Statistical Methods for Multilevel Multivariate Functional StudiesR01NS060910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Ciprian M Crainiceanu · 2009 to 2026
$8.3M
Inter-modal Coupling Image AnalyticsR01MH112847 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Theodore Satterthwaite, Russell Takeshi Shinohara · 2017 to 2026
$5.9M
Statistical methods for large and complex databases of ultra-high-dimensionalR01NS085211 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2013 to 2017
$1.8M
Early detection of Huntington's Disease: Longitudinal analysis of basal ganglia and cortical thicknessR01NS094456 · NINDS · VANDERBILT UNIVERSITY · PI OGUZ, IPEK · 2016 to 2019
$1.3M
NIMH NIH HHS R01 MH112847NINDS NIH HHS R01 NS060910NINDS NIH HHS R01 NS085211NINDS NIH HHS R01 NS094456
6 · The paper itself

Abstract

In this paper, we present a fully convolutional densely connected network (Tiramisu) for multiple sclerosis (MS) lesion segmentation. Different from existing methods, we use stacked slices from all three anatomical planes to achieve a 2.5D method. Individual slices from a given orientation provide global context along the plane and the stack of adjacent slices adds local context. By taking stacked data from three orientations, the network has access to more samples for training and can make more accurate segmentation by combining information of different forms. The conducted experiments demonstrated the competitive performance of our method. For an ablation study, we simulated lesions on healthy controls to generate images with ground truth lesion masks. This experiment confirmed that the use of 2.5D patches, stacked data and the Tiramisu model improve the MS lesion segmentation performance. In addition, we evaluated our approach on the Longitudinal MS Lesion Segmentation Challenge. The overall score of 93.1 places the

Indexed as

Deep learningMultiple sclerosisSegmentation

Identifiers

PMID34950934
PMCPMC8692167

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.