Evidence map›Paper›PMID 34950864›Full record

ReviewEpilepsy & behavior reports2021

Neurostimulation for the treatment of functional neurological disorder: A systematic review.

Irene Gonsalvez, Primavera Spagnolo, Barbara Dworetzky, Gaston Baslet

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Epilepsy & behavior reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06900959 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Transcranial Static Field Stimulation (tSMS) and Transcranial Direct Current Stimulation (tDCS) for the Treatment of Neurological Symptoms

TypeinterventionalSponsorNeuromed IRCCSRan2025 to 2026Enrolled40ConditionsNeurological Diseases or ConditionsArmstranscranial static field stimulation (tSMS) and transcranial (tDCS)
NCT07527403 recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Theta Burst Repetitive Transcranial Magnetic Stimulation on the Patient's Self-reported Improvement in Their Motor Functional Neurological Disorder

TypeobservationalSponsorHospital Center Guillaume RégnierRan2026 to 2028Enrolled22ConditionsFunctional Neurological Disorder, Motor FNDArmstheta-burst rTMS (repetitive transcranial magnetic stimulation)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Neurofeedback for functional neurological disorders: future directions for research and clinical practice.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  2. Treatment of Functional Neurological Disorders.Journal of clinical neurology (Seoul, Korea) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Functional neurological disorder: Practical management.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Irene GonsalvezDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Primavera SpagnoloMary Horrigan Connors Center for Women's Health & Gender Biology, Department of Psychiatry, Brigham and Women Hospital, Harvard Medical School, Boston, MA 02115, USA.
Barbara DworetzkyDepartment of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Gaston BasletDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional Neurological Disorder (FND), also known as conversion disorder, is characterized by neurological symptoms that are incompatible with any known structural disorder and best explained by a biopsychosocial model. Evidence-based treatments for FND are limited, with cognitive behavioral therapy (CBT) and physiotherapy being the most effective interventions [1]. In recent years, functional neuroimaging studies have provided robust evidence of alterations in activity and connectivity in multiple brain networks in FND. This body of evidence suggests that neurocircuitry-based interventions, such as non-invasive brain stimulation techniques (NIBS), may also represent an effective therapeutic option for patients with FND. In this systematic review, we outline the current state of knowledge of NIBS in FND, and discuss limitations and future directions that may help establish the efficacy of NIBS as a therapeutic option for FND.

Indexed as

FNDFunctional seizurestDCSTMS

Identifiers

PMID34950864
PMCPMC8671519

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.