Evidence map›Paper›PMID 34950752›Full record

ArticlePlastic and aesthetic research2021

Platelet-rich plasma for the treatment of lichen sclerosus.

Beija K Villalpando, Saranya P Wyles, Lauren A Schaefer, Katherine J Bodiford, Alison J Bruce

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plastic and aesthetic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Lichen sclerosus: The 2023 update.Frontiers in medicine · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Beija K VillalpandoMayo Clinic Alix School of Medicine, Rochester, MN 55905, USA.
Saranya P WylesDepartment of Dermatology, Mayo Clinic, Rochester, MN 55905 USA.
Lauren A SchaeferMayo Clinic Alix School of Medicine, Rochester, MN 55905, USA.
Katherine J BodifordDepartment of Dermatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Alison J BruceDepartment of Dermatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Mayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

Medical Scientist Traning Program at Mayo ClinicT32GM065841 · NIGMS · MAYO CLINIC ROCHESTER · PI KAUFMANN, SCOTT H, SCHIMMENTI, LISA A · 2003 to 2022
$5.8M
NIGMS NIH HHS T32 GM065841
6 · The paper itself

Abstract

aimEvaluate the clinical effectiveness of platelet-rich plasma as a treatment for lichen sclerosus.

methodsA systematic review was performed. The electronic databases PubMed, Ovid MEDLINE

resultsPlatelet-rich plasma treatment was subjectively reported to improve quality of life, but objective measures demonstrating treatment efficacy were not observed. In addition, platelet-rich plasma preparation and administration between studies lacked standardization.

conclusionPlatelet-rich plasma may be used for symptomatic adjuvant treatment of lichen sclerosus, though additional double-blind controlled studies with standardized platelet-rich plasma protocols are needed to better characterize the efficacy of platelet-rich plasma.

Indexed as

lichen sclerosuspenile lichen sclerosusPlatelet rich plasmavulvar lichen sclerosus

Identifiers

PMID34950752
PMCPMC8694569
OpenAlexW4200036348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.