Evidence map›Paper›PMID 34950646›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Evaluation of Bi-Layer Silk Fibroin Grafts for Penile Tunica Albuginea Repair in a Rabbit Corporoplasty Model.

Gokhan Gundogdu, Zhamshid Okhunov, Stephanie Starek, Faith Veneri, Hazem Orabi, Sarah A Holzman, Maryrose P Sullivan, Antoine E Khoury, Joshua R Mauney

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Characterization of a novel rabbit model of Peyronie's disease.International journal of impotence research · 2024
    Article
  4. Tissue Engineering for Penile Reconstruction.Bioengineering (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Gokhan GundogduDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Zhamshid OkhunovDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Stephanie StarekDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Faith VeneriDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Hazem OrabiDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Sarah A HolzmanDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Maryrose P SullivanDepartment of Surgery and Harvard Medical School, Boston, MA, United States.
Antoine E KhouryDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
Joshua R MauneyDepartment of Urology, University of California, Irvine, Irvine, CA, United States.
University of California, Irvine · USChildren's Hospital of Orange County · USHarvard University · US

Funding

Partial Bladder Outlet Obstruction: Mechanisms of Injury and Novel Repair StrategiesR01DK119240 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI ESTRADA, CARLOS R, MAUNEY, JOSHUA ROBERT · 2019 to 2023
$1.6M
NIDDK NIH HHS R01 DK119240
6 · The paper itself

Abstract

The use of autologous tissue grafts for tunica albuginea repair in Peyronie's disease and congenital chordee is often restricted by limited tissue availability and donor site morbidity, therefore new biomaterial options are needed. In this study, bi-layer silk fibroin (BLSF) scaffolds were investigated to support functional tissue regeneration of tunica albuginea in a rabbit corporoplasty model. Eighteen adult male, New Zealand white rabbits were randomized to nonsurgical controls (NSC,

Indexed as

biomaterialscorporoplastyregenerationsilk fibrointissue engineering

Identifiers

PMID34950646
PMCPMC8688800
OpenAlexW4200401179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.