Evidence map›Paper›PMID 34950589›Full record

ReviewFrontiers in oncology2021

Current Surgical Therapy of Locally Advanced cSCC: From Patient Selection to Microsurgical Tissue Transplant. Review.

Tito Brambullo, Gian Paolo Azzena, Paolo Toninello, Giuseppe Masciopinto, Alberto De Lazzari, Bernardo Biffoli, Vincenzo Vindigni, Franco Bassetto

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tito BrambulloClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Gian Paolo AzzenaClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Paolo ToninelloClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Giuseppe MasciopintoClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Alberto De LazzariClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Bernardo BiffoliClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Vincenzo VindigniClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.
Franco BassettoClinic of Plastic Surgery, Department of Neurosciences, Padua University Hospital, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the non-melanoma skin cancers (NMSC) the squamous cell carcinoma (SCC) is one of the most challenging for the surgeon. Local aggressiveness and a tendency to metastasize to regional lymph nodes characterize the biologic behavior. The variants locally advanced and metastatic require wide excision and node dissection. Such procedures can be extremely detrimental for patients. The limit of the surgery can be safely pushed forward with a multidisciplinary approach. The concept of skin oncoplastic surgery, the ablative procedures and the reconstructive options (skin graft, pedicled flap, microsurgical free flap) are discussed together with a literature review.

Indexed as

locally advanced diseasemicrosurgerynon-melanoma skin canceroncoplasticreconstructive surgerySCCskin oncoplastic surgerysquamous cell carcinoma

Identifiers

PMID34950589
PMCPMC8690035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.