Evidence map›Paper›PMID 34950521›Full record

ArticleCase reports in genetics2021

A Chinese Patient with Spastic Paraplegia Type 4 with a

Li Xu, Zijuan Peng, Chunhui Zhou, Jiqing Wang, Hunjin Luo, Qin Lu, Zhengjun Bao

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Li XuAntenatal Diagnosis Center of Women and Children Healthcare Hospital of ZHUZHOU, Zhouzhou, Hunan 412000, China.ORCID https://orcid.org/0000-0001-9790-1259
Zijuan PengCentral Hospital of ZHUZHOU, Affiliated Zhuzhou Hospital of Xiangya School of Medicine, Central South University, Zhouzhou, Hunan 412000, China.
Chunhui ZhouWomen and Children Healthcare Hospital of ZHUZHOU, Zhouzhou, Hunan 412000, China.
Jiqing WangWomen and Children Healthcare Hospital of ZHUZHOU, Zhouzhou, Hunan 412000, China.
Hunjin LuoWomen and Children Healthcare Hospital of ZHUZHOU, Zhouzhou, Hunan 412000, China.
Qin LuGeneTalks Biotech Co., Ltd., Changsha, Hunan 410000, China.
Zhengjun BaoCentral Hospital of ZHUZHOU, Affiliated Zhuzhou Hospital of Xiangya School of Medicine, Central South University, Zhouzhou, Hunan 412000, China.ORCID https://orcid.org/0000-0003-4988-5164
Zhuzhou Central Hospital · CNCentral South University · CNXiangnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpastic paraplegia type 4 (SPG4) is the most common type of hereditary spastic paraplegia (HSP) caused by mutations in the SPAST gene.

conclusionIn this report, we identified a missense mutation in the SPAST gene (p.Arg499His) in a 27-year-old pregnant Chinese woman with HSP. We believe that this study expands the knowledge about the clinical parameters and mutation spectrum of SPG4.

Identifiers

PMID34950521
PMCPMC8692052
OpenAlexW4200380960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.