Evidence map›Paper›PMID 34950389›Full record

ArticleThe Neurohospitalist2022

Reversal of Stroke-Like Episodes With L-Arginine and Meticulous Perioperative Management of Renal Transplantation in a Patient With Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) Syndrome. Case Report.

Ghalia Al Yazidi, Jaap Mulder, Christoph Licht, Elizabeth Harvey, James Robertson, Neal Sondheimer, Ingrid Tein

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Neurohospitalist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Identification ofFrontiers in molecular biosciences · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ghalia Al YazidiDivision of Neurology, The Hospital for Sick Children, Toronto, Canada.
Jaap MulderDivision of Nephrology, The Hospital for Sick Children, Toronto, Canada.
Christoph LichtDivision of Nephrology, The Hospital for Sick Children, Toronto, Canada.
Elizabeth HarveyDivision of Nephrology, The Hospital for Sick Children, Toronto, Canada.
James RobertsonDepartment of Anesthesiology, The Hospital for Sick Children, Toronto, Canada.
Neal SondheimerDivision of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, Canada.
Ingrid TeinDivision of Neurology, The Hospital for Sick Children, Toronto, Canada.ORCID https://orcid.org/0000-0002-5739-3162
Hospital for Sick Children · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial encephalomyopathy, lactic acidosis and stroke like episodes (MELAS) syndrome is a maternally inherited mitochondrial disorder with recurrent non-arterial distribution stroke-like episodes (SLEs). A 17 yr old boy with MELAS (m.3243A>G tRNA

Indexed as

case reportchronic renal failureencephalopathylactic acidosis and stroke-like episodes)L-arginineMELAS (mitochondrial encephalomyopathymitochondriarenal transplantstrokestroke like episodes

Identifiers

PMID34950389
PMCPMC8689537
OpenAlexW3137064755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.