Evidence map›Paper›PMID 34950386›Full record

ArticleThe Neurohospitalist2022

Healthcare Worker With Large Vessel Acute Ischemic Stroke Likely Related to Mild SARS-CoV-2 Infection.

Carlos Castillo-Pinto, Guillaume Lamotte, Amit Mehta, Rajiv Sonti, Gianluca Di Maria, Daniel Ruiz, Princy N Kumar, Andrew B Stemer, M Carter Denny

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Neurohospitalist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Carlos Castillo-PintoDepartment of Pediatric Neurology, Children's National Medical Center, Washington, DC, USA.ORCID https://orcid.org/0000-0002-5228-8574
Guillaume LamotteGeorgetown University Medical Center, Washington, DC, USA.ORCID https://orcid.org/0000-0003-4048-6095
Amit MehtaGeorgetown University Medical Center, Washington, DC, USA.ORCID https://orcid.org/0000-0001-5721-9589
Rajiv SontiGeorgetown University Medical Center, Washington, DC, USA.
Gianluca Di MariaGeorgetown University Medical Center, Washington, DC, USA.
Daniel RuizGeorgetown University Medical Center, Washington, DC, USA.
Princy N KumarGeorgetown University Medical Center, Washington, DC, USA.
Andrew B StemerGeorgetown University Medical Center, Washington, DC, USA.
M Carter DennyGeorgetown University Medical Center, Washington, DC, USA.ORCID https://orcid.org/0000-0002-7003-1748
Georgetown University · USChildren's National · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a healthcare worker who presented with a large vessel acute ischemic stroke in setting of a mild SARS-CoV-2 infection and provide a review of the emerging literature on COVID-related stroke. A 43-year-old female presented with right-sided hemiparesis, aphasia and dysarthria. She had a nonproductive of cough for 1 week without fever, fatigue or dyspnea. A CT Head, CT angiography and CT perfusion imaging revealed a M1 segment occlusion of the left middle cerebral artery requiring transfer from a primary to a comprehensive stroke center. A nasopharyngeal swab confirmed SARS-CoV-2 infection prior to arrival at the accepting center. During the thrombectomy a 3 cm thrombus was removed. Thrombus was also evident in the 8 French short sheath during closure device placement so a hypercoagulable state was suspected. Stroke work-up revealed a glycosylated hemoglobin of 8.7%, elevation of inflammatory markers and an indeterminate level of lupus anticoagulant IgM. On discharge home, she had near complete neurological recovery. This case highlights suspected mechanisms of hypercoagulability in SARS-CoV-2 infection and the importance of optimizing stroke care systems during the COVID-19 pandemic.

Indexed as

acute ischemic strokeCOVID-19hypercoagulable statelarge vessel occlusionSARS-CoV-2strokesystem of carethrombectomy

Identifiers

PMID34950386
PMCPMC8689530
OpenAlexW3102723905

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.