Evidence map›Paper›PMID 34950369›Full record

ArticleJournal of atrial fibrillation2021

Contact-Force Guided Posterior Wall Isolation as an Adjunctive Ablation Strategy for Persistent Atrial Fibrillation.

Giusy Sirico, Domenico Sirico, Andrea Montisci, Enrico Cerrato, Martina Morosato, Stefania Panigada, Luca Ottaviano, Valerio De Sanctis, Massimo Mantica

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of atrial fibrillation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Giusy SiricoDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Domenico SiricoPediatric and Congenital Cardiology Unit, Department of Woman and Child's Health, University of Padova, Padova, Italy.
Andrea MontisciDepartment of Anesthesia and Intensive Care, Cardiothoracic Center, Istituto Clinico Sant'Ambrogio, Milan, Italy and Chair of Cardiac Surgery, Postgraduate in Cardiac Surgery, University of Milan, Italy.
Enrico CerratoInterventional Unit, San Luigi Gonzaga University Hospital, Orbassano and Infermi Hospital, Rivoli (Torino), Italy and Chair of Cardiac Surgery, Postgraduate in Cardiac Surgery, University of Milan, Italy.
Martina MorosatoDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Stefania PanigadaDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Luca OttavianoDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Valerio De SanctisDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Massimo ManticaDepartment of Cardiac Electrophysiologist and Pacing, Istituto Clinico Sant'Ambrogio, Milan, Italy.
Istituto Clinico Sant'Ambrogio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy of posterior wall isolation (PWI) on top of pulmonary vein isolation (PVI) in patients affected by persistent atrial fibrillation (AF) is still controversial and little is known about the impact of contact-force (CF) technology.

objectiveIn this retrospective study, we present our experience with PWI using CF sensing catheters and its efficacy and safety as an adjunctive ablation strategy on top of PVI for management of patients with persistent and longstanding persistent AF.

methodsA total of 73 consecutive patients (20.5% female) affected by persistent atrial fibrillation (10.9% long-standing) underwent PWI as an adjunctive therapy to PVI using CF sensing catheters. Outcomes were reported as incidence of atrial arrhythmic recurrences (ARs) lasting >30 seconds at follow up and in addition, in patients provided with insertable cardiac monitors (ICM), as burden of AF or atrial tachycardias (AT) at relevant time points.

resultsPWI was successfully achieved in 65 (89.0%) patients. Two (2.7%) minor vascular procedural complications were observed. At 1 and 2-year follow-up, ARs free survival was observed in 80.5% and 64.1% of patients, respectively with 75.3% of patients off antiarrhythmic drugs at the last follow-up. Ten patients underwent repeat ablations during the follow-up. At multivariate analysis, early ARs within 3 months after procedure, were associated with a two-fold increased risk of late ARs at follow-up. Among patients provided with ICM, PWI on top of PVI was able to reduce the mean AT/AF burden of more than 50% compared with pre-ablation time, reporting very low levels (≤ 5%) over 2 years.

conclusionsIn persistent atrial fibrillation, PWI on top of PVI using CF sensing catheters is safe and effective, providing great reduction of burden of ARs. Early ARs are associated with a greater risk of late recurrences.

Indexed as

AF BurdenContact ForceEarly RecurrencePersistent Atrial FibrillationPosterior Wall Isolation

Identifiers

PMID34950369
PMCPMC8691276
OpenAlexW4206830546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.