Evidence map›Paper›PMID 34950340›Full record

ArticleJournal of atrial fibrillation

Impact of Afterload-Integrated Diastolic Indexon Prognosis in Elderly Patients with Heart Failure with Preserved Ejection Fraction with and without Atrial Fibrillation.

Shiro Hoshida, Yukinori Shinoda, Koichi Tachibana, Tomoko Minamisaka, Takahisa Yamada, Yoshio Yasumura, Shunsuke Tamaki, Takaharu Hayashi, Masamichi Yano, Shungo Hikoso and 1 more

Abstract read
In one paragraph

Article in Journal of atrial fibrillation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shiro HoshidaDepartment of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Japan.
Yukinori ShinodaDepartment of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Japan.
Koichi TachibanaDepartment of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Japan.
Tomoko MinamisakaDepartment of Cardiovascular Medicine, Yao Municipal Hospital, Yao, Japan.
Takahisa YamadaDivision of Cardiology, Osaka General Medical Center, Osaka, Japan.
Yoshio YasumuraDivision of Cardiology, Amagasaki Chuo Hospital, Amagasaki, Japan.
Shunsuke TamakiDivision of Cardiology, Osaka General Medical Center, Osaka, Japan.
Takaharu HayashiCardiovascular Division, Osaka Police Hospital, Osaka, Japan.
Masamichi YanoDivision of Cardiology, Osaka Rosai Hospital, Sakai, Japan.
Shungo HikosoDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Yasushi SakataDepartment of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectsWe aimed to clarify the differences in the of the ratio of diastolic elastance (Ed) to arterial elastance (Ea), [Ed/Ea=(E/e')/(0.9×systolic blood pressure)], anafterload-integrateddiastolic index that reflects left atrial pressure overload, on prognosis between patients with heart failure with preserved ejection fraction (HFpEF) with and without atrial fibrillation (AF).

methodsWe studied 552 HFpEF patients hospitalized for acute decompensated heart failure (sinus rhythm/AF:352/200).Blood testing and transthoracic echocardiography were performed before discharge. Primary endpoint was all-cause mortality after discharge.

resultsDuring a median follow-up of 508 days, 88 patients (sinus rhythm/AF: 54/34) had all-cause mortality. In the subgroup with sinus rhythm, but not AF, Ed/Ea was significantly higher in patients with than without all-cause mortality. In a multivariate Cox hazard analysis, Ed/Ea was significantly associated with all-cause mortality independent of N-terminal pro-brain natriuretic peptide level in patients with sinus rhythm, but not with AF.

conclusionsEd/Ea providedlesser important information for predicting all-cause mortality in HFpEF patients with AF than with sinus rhythm. The prognostic risk factors may differ between elderly HFpEF patients with and without AF.

Indexed as

Atrial fibrillationDiastolic functionLeft atrial overloadNT-proBNP

Identifiers

PMID34950340
PMCPMC8691356

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.