Evidence map›Paper›PMID 34950044›Full record

ArticleFrontiers in physiology2021

Computational Modelling of Glucose Uptake by SGLT1 and Apical GLUT2 in the Enterocyte.

Nima Afshar, Soroush Safaei, David P Nickerson, Peter J Hunter, Vinod Suresh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nima AfsharAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Soroush SafaeiAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
David P NickersonAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Peter J HunterAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Vinod SureshAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
University of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been suggested that glucose absorption in the small intestine depends on both constitutively expressed SGLT1 and translocated GLUT2 in the brush border membrane, especially in the presence of high levels of luminal glucose. Here, we present a computational model of non-isotonic glucose uptake by small intestinal epithelial cells. The model incorporates apical uptake

Indexed as

CellMLepithelial transportglucose absorptionnutrient absorptionOpenCORtype 2 diabetes

Identifiers

PMID34950044
PMCPMC8688934
OpenAlexW4200249272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.