Evidence map›Paper›PMID 34950042›Full record

ArticleFrontiers in pharmacology2021

Sempervirine Inhibits Proliferation and Promotes Apoptosis by Regulating Wnt/β-Catenin Pathway in Human Hepatocellular Carcinoma.

Rongcai Yue, Haiping Liu, Yaxin Huang, Jing Wang, Dongmei Shi, Yanping Su, Yufei Luo, Ping Cai, Guilin Jin, Changxi Yu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Effects of the Polar Fraction ofInternational journal of molecular sciences · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Rongcai YueSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Haiping LiuSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Yaxin HuangSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Jing WangSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Dongmei ShiSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Yanping SuSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Yufei LuoSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Ping CaiFujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China.
Guilin JinSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Changxi YuSchool of Pharmacy, Fujian Medical University, Fuzhou, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alkaloidsGelsemium elegans benth.hepatocellular carcinomasempervirinewnt/β-catenin

Identifiers

PMID34950042
PMCPMC8689006
OpenAlexW4200120316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.