Evidence map›Paper›PMID 34950013›Full record

ArticleCase reports in ophthalmology

Diplopia as the First Sign of Gastric Carcinoma.

Suzanna L Roohé, Ivan M Gan, Kim van der Weerd, Boaz Lopuhaä, Robert M Verdijk, Dion Paridaens

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Suzanna L RoohéDepartment of Oculoplastic and Orbital Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Ivan M GanDepartment of Ophthalmology, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Kim van der WeerdDepartment of Internal Medicine, Franciscus Gasthuis & Vlietland, Rotterdam, The Netherlands.
Boaz LopuhaäDepartment of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Robert M VerdijkDepartment of Pathology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Dion ParidaensDepartment of Oculoplastic and Orbital Surgery, The Rotterdam Eye Hospital, Rotterdam, The Netherlands.
Erasmus MC · NLSint Franciscus Gasthuis · NLRotterdam Eye Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carcinoma to an extraocular eye muscle is extremely rare. A solitary thickening in an extraocular eye muscle with no inflammatory features is suspect for a tumor. Symptoms such as diplopia, proptosis, ptosis, vision loss, or pain may be associated with an orbital malignancy. Our patient, a 67-year-old man known with radically resected prostate cancer, presented with complaints of vertigo with a tendency to fall, headache, and diplopia when looking to the right. As a coincidental finding, swelling of the rectus lateralis muscle of the left eye was observed on imaging. Extensive additional investigations showed that a gastric carcinoma with intraorbital and leptomeningeal metastasis was the cause. In conclusion, a solitary thickened extraocular eye muscle should be recognized in time and examined further.

Indexed as

DiplopiaExtraocular muscleGastric carcinomaOrbital metastases

Identifiers

PMID34950013
PMCPMC8647119
OpenAlexW3209551347

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.