ArticleInternational journal of chronic obstructive pulmonary disease
Anxiety and Depression in Patients with Chronic Obstructive Pulmonary Disease in China: Results from the China Pulmonary Health [CPH] Study.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 23 citations in OpenAlex.
- Effectiveness of village doctors led cognitive behavioral therapy for COPD patients in a randomized controlled trial.Scientific reports · 2025Trial
- Prevalence of anxiety and depression and diagnostic utility of the CAT scale in spirometry-confirmed COPD patients: Findings from the Chinese Population Health and Multimorbidities Study.Chinese medical journal pulmonary and critical care medicine · 2026Article
- Construction of a prediction model for depression risk in elderly patients with chronic obstructive pulmonary disease based on machine learning algorithms and analysis of influencing factors.Scientific reports · 2026Article
- Disability in Older Adults with COPD: Prevalence, Assessment, and Influencing Factors - A Scoping Review.Clinical interventions in aging · 2026Article
- Socioeconomic differences in prevalence and patterns of non-communicable disease multimorbidity and its impact on depression in rural Southwest China.Preventive medicine reports · 2025Article
- Validation of the patient health questionnaire (PHQ)-9 and PHQ-2 in patients with COPD in China.BMC psychiatry · 2025Article
- Prevalence and correlates of anxiety disorders and depressive disorders among older adults with non-communicable diseases: results from China Mental Health Survey.Frontiers in psychiatry · 2025Article
- Effects of the teach-back method on the health status of patients with chronic obstructive pulmonary disease: a real-world community-based cluster-randomized controlled trial.Journal of thoracic disease · 2024Article
- Prevalence and risk factors of depression in patients with chronic obstructive airway disease: a tertiary care hospital, outpatient setting.Multidisciplinary respiratory medicine · 2024Article
- Heterogeneities and impact profiles of early chronic obstructive pulmonary disease status: findings from the China Pulmonary Health Study.The Lancet regional health. Western Pacific · 2024Article
- Efficacy and safety of a music-therapy facilitated pulmonary telerehabilitation program in COPD patients: the COPDMELODY study protocol.Frontiers in medicine · 2024Article
- Risk factors for anxiety and its impacts on acute exacerbation in older patients with chronic obstructive pulmonary disease.Frontiers in medicine · 2024Article
- Anxiety and Depression in Patients With Chronic Respiratory Diseases in the Fès-Meknès Region of Morocco.Cureus · 2023Article
- Fatigue, Depression, and Anxiety in Patients with COPD, Asthma and Asthma-COPD Overlap.Journal of clinical medicine · 2022Article
- Impact of the Coronavirus Disease 2019 Pandemic on Physical and Mental Health of Patients With COPD: Results From a Longitudinal Cohort Study Conducted in the United States (2020-2021).Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Article
- Effectiveness and cost-effectiveness of an integrated digital psychological intervention (Digital healthArticle
- Associations between depression and anxiety index and frequency of acute exacerbation in chronic obstructive pulmonary disease.Therapeutic advances in respiratory diseaseArticle
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Authors and funding
18 authors at 14 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAnxiety and depression are often underdiagnosed and affect the prognosis of patients with chronic obstructive pulmonary disease (COPD). We analyzed data from the China Pulmonary Health (CPH) study to assess the prevalence of anxiety and depression in COPD patients and their relationship with disease severity. PATIENTS AND
methodsA total of 57,779 subjects aged 20 years or older were recruited in the CPH study. All participants were assessed using a standard questionnaire and underwent pulmonary function tests before and after the use of a bronchodilator in local health centers. The Hospital Anxiety and Depression Scale (HADS) questionnaire with a cutoff score of 8 was used to define anxiety and depression. The prevalence of anxiety and depression in patients of COPD were investigated. Multivariate logistic regression was used to investigate the effects of COPD and lung function on anxiety and depression.
resultsA total of 49,053 participants (20,661 men and 28,392 women) completed the questionnaire with reliable post-bronchodilator pulmonary function test results and were included in the final analysis, of which 4686 (9.55%) were diagnosed with COPD. Of the patients with COPD, 10.79% had anxiety, 13.65% had depression, and 7.08% had anxiety and depression concomitantly. In the multivariate logistic regression analysis, COPD was not significantly associated with anxiety, depression, or both. After adjusting for confounders in model 1, patients in the GOLD III-IV group had a significantly higher risk of anxiety, depression, and their coincidence. After further adjusting for respiratory symptoms in model 2, lung function impairment in the GOLD III-IV group was only significantly associated with a higher risk of depression or at least one of anxiety and depression.
conclusionAnxiety and depression are prevalent in patients with COPD in China. More severe lung function impairment is significantly associated with a higher risk of depression.
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