ArticleJSLS : Journal of the Society of Laparoendoscopic Surgeons
Tissue Reaction and the Formation of Adhesion after the Use of DS Clip in Laparoscopic Appendectomy.
Article in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Modified single-site two-port laparoscopic appendectomy with single-instrument knotting and absorbable clips in children: a retrospective study.Frontiers in pediatrics · 2026Article
- Novel clipping procedure for preventing post-operative inguinal hernia in robot-assisted radical prostatectomy.International journal of urology : official journal of the Japanese Urological Association · 2024Article
- Clips closure versus endoloop ligation in laparoscopic appendectomy: a systematic review and meta-analysis of comparative studies.Annals of medicine and surgery (2012) · 2023Review
- Is the Choice Between Clips and No Clips or Cautery and No Cautery Still a Dilemma in Robot-assisted Radical Prostatectomy?European urology open science · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesTitanium DS clips are made to secure the appendiceal stump during laparoscopic appendectomy. The assumption is that they behave like stapler clips in the body, being made from titanium. However, the construction and weight of DS clips differs from staplers. Their biocompatibility may have implications for their clinical use.
methodsOne hundred and twenty rats were randomized into four experimental groups: in the first group the appendiceal stump was secured by Vicryl® ligature, in the second by linear staplers, in the third by Hem-o-lok® plastic clips, and in the fourth by DS titanium clips. Ten animals from each group were sacrificed 7, 28, and 60 days post-surgery. Histopathological data and adhesion formation were assessed.
resultsOn postoperative day 7, a statistically significant difference was found in the occurrence of inflammation between the Hem-o-lok® and stapler groups. The adhesion score was significantly higher in the Vycril® and Hem-o-lok® in comparison to the DS and stapler groups. On postoperative day 28, a statistically significant difference was found in the occurrence of inflammation between the Vycril® and stapler groups. The adhesion score was significantly higher in the Vycril® than in the DS and stapler groups. On postoperative day 60, there were no statistical differences between any of the groups. The adhesion score was significantly higher in the Hem-o-lok® group in comparison to the DS and stapler groups.
conclusionStaplers and DS clips have advantages over other methods of securing the appendiceal stump, because of their high biocompatibility and lower adhesion score.
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Registered trials
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