ArticleNature human behaviour2022
A mixed-methods, population-based study of a syndemic in Soweto, South Africa.
Article in Nature human behaviour, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gender-based violence syndemics in global health: A systematic review.Social science & medicine (1982) · 2025Pooled it
- Examining the length of hospital stay and associated factors in adult patients with schizophrenia.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
- A qualitative study of the social and structural vulnerabilities of HIV and chronic disease syndemics in low-resource urban health facilities in South Africa.Discover public health · 2026Article
- Multimorbidity and health system priorities in Zimbabwe: A participatory ethnographic study.PLOS global public health · 2025Article
- Convergence between Cardiometabolic and Infectious Diseases in Adults from a Syndemic Perspective: A Scoping Review.Tropical medicine and infectious disease · 2024Article
- The Economic Burden of Chronic Diseases with Co-Occurring Depression and Alcohol Use Disorder for People in the Western Cape, South Africa.SSM. Mental health · 2023Article
- Factors affecting ability of TB patients to follow treatment guidelines - applying a capability approach.International journal for equity in health · 2023Article
- Syndemic thinking to address multimorbidity and its structural determinants.Nature reviews. Disease primers · 2023Article
- Intervening on the Intersecting Issues of Intimate Partner Violence, Substance Use, and HIV: A Review of Social Intervention Group's (SIG) Syndemic-Focused Interventions for Women.Research on social work practice · 2023Article
- What works in engaging communities? Prioritising nutrition interventions in Burkina Faso, Ghana and South Africa.PloS one · 2023Article
- Flourishing with chronic illness(es) and everyday stress: Experiences from Soweto, South Africa.Wellbeing, space and society · 2023Article
- Syndemics and clinical science.Nature medicine · 2022Review
- Context, COVID-19 and comorbidities: exploring emergent directions in syndemics and HIV research.Current opinion in HIV and AIDS · 2022Review
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Abstract
A syndemic has been theorized as a cluster of epidemics driven by harmful social and structural conditions wherein the interactions between the constitutive epidemics drive excess morbidity and mortality. We conducted a mixed-methods study to investigate a syndemic in Soweto, South Africa, consisting of a population-based quantitative survey (N = 783) and in-depth, qualitative interviews (N = 88). We used ethnographic methods to design a locally relevant measure of stress. Here we show that multimorbidity and stress interacted with each other to reduce quality of life. The paired qualitative analysis further explored how the quality-of-life impacts of multimorbidity were conditioned by study participants' illness experiences. Together, these findings underscore the importance of recognizing the social and structural drivers of stress and how they affect the experience of chronic illness and well-being.
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