Evidence map›Paper›PMID 34949654›Full record

ReviewCancer genomics & proteomics

The Application of Bayesian Methods in Cancer Prognosis and Prediction.

Jiadong Chu, N A Sun, Wei Hu, Xuanli Chen, Nengjun Yi, Yueping Shen

Abstract readReview
In one paragraph

Review in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
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  6. Article
  7. Review
  8. A guide to multi-omics data collection and integration for translational medicine.Computational and structural biotechnology journal · 2023
    Review
  9. Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiadong ChuDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, P.R. China.
N A SunDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, P.R. China.
Wei HuDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, P.R. China.
Xuanli ChenDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, P.R. China.
Nengjun YiDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, U.S.A.
Yueping ShenDepartment of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, P.R. China; shenyueping@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of high-throughput biological techniques, high-dimensional omics data have emerged. These molecular data provide a solid foundation for precision medicine and prognostic prediction of cancer. Bayesian methods contribute to constructing prognostic models with complex relationships in omics and improving performance by introducing different prior distribution, which is suitable for modelling the high-dimensional data involved. Using different omics, several Bayesian hierarchical approaches have been proposed for variable selection and model construction. In particular, the Bayesian methods of multi-omics integration have also been consistently proposed in recent years. Compared with single-omics, multi-omics integration modelling will contribute to improving predictive performance, gaining insights into the underlying mechanisms of tumour occurrence and development, and the discovery of more reliable biomarkers. In this work, we present a review of current proposed Bayesian approaches in prognostic prediction modelling in cancer.

Indexed as

Models, BiologicalBayes TheoremBiomarkers, TumorGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMetabolomicsNeoplasmsPrecision MedicinePrognosisProteomicsBiomarkers, TumorBayesiancancerintegrativemulti-omicsprognosisreviewsingle-omicssurvival

Identifiers

PMID34949654
PMCPMC8717957

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.