Evidence map›Paper›PMID 34949510›Full record

Observational studyClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2022

Association between first language and SARS-CoV-2 infection rates, hospitalization, intensive care admissions and death in Finland: a population-based observational cohort study.

Ville Holmberg, Heli Salmi, Salla Kattainen, Jukka Ollgren, Anu Kantele, Juulia Pynnönen, Asko Järvinen, Erik Forsblom, Suvi Silén, Sanna-Maria Kivivuori and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Revista panamericana de salud publica = Pan American journal of public health · 2026
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  3. Revista panamericana de salud publica = Pan American journal of public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ville HolmbergDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. Electronic address: ville.holmberg@hus.fi.
Heli SalmiDepartment of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Salla KattainenDepartment of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Jukka OllgrenDepartment of Health Security, Finnish Institute for Health and Welfare (THL), Finland.
Anu KanteleDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Juulia PynnönenDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Asko JärvinenDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Erik ForsblomDepartment of Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Suvi SilénDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Sanna-Maria KivivuoriHelsinki University Hospital, Helsinki, Finland.
Atte MeretojaGeneral Administration, Helsinki University Hospital, Helsinki, Finland.
Johanna HästbackaDepartment of Anaesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMotivated by reports of increased risk of coronavirus disease 2019 (COVID-19) in ethnic minorities of high-income countries, we explored whether patients with a foreign first language are at an increased risk of COVID-19 infections, more serious presentations, or worse outcomes.

methodsIn a retrospective observational population-based quality registry study covering a population of 1.7 million, we studied the incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), admissions to specialist healthcare and the intensive care unit (ICU), and all-cause case fatality in different language groups between 27th February and 3rd August 2020 in Southern Finland. A first language other than Finnish, Swedish or Sámi served as a surrogate marker for a foreign ethnic background.

resultsIn total, 124 240 individuals were tested, and among the 118 300 (95%) whose first language could be determined, 4005 (3.4%) were COVID-19-positive, 623 (0.5%) were admitted to specialized hospitals, and 147 (0.1%) were admitted to the ICU; 254 (0.2%) died. Those with a foreign first language had lower testing rates (348, 95%CI 340-355 versus 758, 95%CI 753-762 per 10 000, p < 0.0001), higher incidence (36, 95%CI 33-38 versus 22, 95%CI 21-23 per 10 000, p < 0.0001), and higher positivity rates (103, 95%CI 96-109 versus 29, 95%CI 28-30 per 1000, p < 0.0001). There was no significant difference in ICU admissions, disease severity at ICU admission, or ICU outcomes. Case fatality by 90 days was 7.7% in domestic cases and 1.2% in those with a foreign first language, explained by demographics (age- and sex-adjusted HR 0.49, 95%CI 0.21-1.15).

conclusionsThe population with a foreign first language was at an increased risk for testing positive for SARS-CoV-2, but when hospitalized they had outcomes similar to those in the native, domestic language population. This suggests that special attention should be paid to the prevention and control of infectious diseases among language minorities.

Indexed as

COVID-19Cohort StudiesCritical CareEthnic and Racial MinoritiesFinlandHospitalizationHumansIntensive Care UnitsLanguageRetrospective StudiesCOVID-19EthnicLanguageMigrantsMinoritySARS-CoV-2Vulnerable

Identifiers

PMID34949510
PMCPMC8482016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.