Observational studyRespiratory research2021
Overnight variation in tidal expiratory flow limitation in COPD patients and its correction: an observational study.
Observational study in Respiratory research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04725500 (Engineering Evaluation of the Vector NIV Device in Chronic Obstructive Pulmonary Disease), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Engineering Evaluation of the Vector NIV Device in Chronic Obstructive Pulmonary Disease (COPD) Patients
Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Ondansetron: a potential intervention for improving clinical outcomes in stroke patients.Frontiers in pharmacology · 2025Article
- Still no room to breathe: insights on supine lung mechanics from oscillometry in COPD.ERJ open research · 2024Article
- Deventilation Syndrome in Patients with Chronic Obstructive Pulmonary Disease Using Nocturnal Noninvasive Ventilation: What Are the Underlying Mechanisms?Respiration; international review of thoracic diseases · 2024Observational
- Ventilators, Settings, Autotitration Algorithms.Journal of clinical medicine · 2023Review
- Supplemental oxygen and noninvasive ventilation.European respiratory review : an official journal of the European Respiratory Society · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTidal expiratory flow limitation (EFL
methodsCOPD patients considered for noninvasive ventilation used a ventilator which measured within-breath reactance change at 5 Hz (∆Xrs) and adjusted EPAP settings to abolish EFL
resultsOf 26 patients with supine EFL
conclusionsTidal expiratory flow limitation varies significant during sleep in COPD patients. This can be controlled by auto-titrating the amount of EPAP delivered. This approach appears to be practical and well tolerated by patients.
trial registrationThe trial was retrospectively registered at CT.gov NCT04725500.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.