Evidence map›Paper›PMID 34948770›Full record

ArticleInternational journal of environmental research and public health2021

Relationship between Physical Activity and the Metabolic, Inflammatory Axis in Pregnant Participants.

Adeline Bockler, Nina Ferrari, Clara Deibert, Anne Flöck, Waltraut M Merz, Ulrich Gembruch, Christina Ehrhardt, Jörg Dötsch, Christine Joisten

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Adeline BocklerDepartment of General Internal Medicine/Cardiology, Marienhof Hospital, Rudolf-Virchow-Str. 7-9, 56073 Koblenz, Germany.
Nina FerrariCologne Center for Prevention in Childhood and Youth/Heart Center Cologne, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Clara DeibertDepartment of Pediatric, DRK Hospital Kirchen, Bahnhofstraße 24, 57548 Kirchen, Germany.
Anne FlöckDepartment of Obstetrics and Prenatal Medicine, University Bonn Medical School, Venusberg-Campus 1, 53127 Bonn, Germany.
Waltraut M MerzDepartment of Obstetrics and Prenatal Medicine, University Bonn Medical School, Venusberg-Campus 1, 53127 Bonn, Germany.
Ulrich GembruchDepartment of Obstetrics and Prenatal Medicine, University Bonn Medical School, Venusberg-Campus 1, 53127 Bonn, Germany.
Christina EhrhardtDepartment for Physical Activity in Public Health, Institute of Movement and Neurosciences, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany.
Jörg DötschDepartment of Pediatrics and Adolescent Medicine, Faculty of Medicine, University Hospital Cologne and University of Cologne, Robert-Koch-Str. 16, 50931 Cologne, Germany.
Christine JoistenDepartment for Physical Activity in Public Health, Institute of Movement and Neurosciences, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany.ORCID 0000-0002-2455-8901
German Sport University Cologne · DEUniversity of Bonn · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) during pregnancy is beneficial for mother and child. Little is known regarding the effects of PA on specific adipokines/myokines and their impact during pregnancy. This study investigates the correlation between PA during late pregnancy, body composition, and maternal levels of leptin, IL-6, and TNF-α at delivery. In a cross-sectional study of 91 pregnant participants (mean age 33.9 ± 4.6 years) without gestational diabetes mellitus or preeclampsia, anthropometric data and blood samples were taken at delivery. PA during the third trimester was measured via the Pregnancy Physical Activity Questionnaire. Activities were ranked by intensity: sedentary (<1.5 metabolic equivalent (METs)), light (1.5-3.0 METs), moderate (3.0-6.0 METs), and vigorous activity (>6.0 METs). Leptin at delivery correlated positively with body composition and negatively with light PA intensity. Sedentary behaviour showed a positive correlation with IL-6 levels at delivery. Moderate activity during the last trimester, sedentary activity levels, and body composition had the greatest influence on maternal IL-6 at delivery. Completed weeks of pregnancy, moderate and light PA, and sedentary activity had the greatest influence on maternal TNF-α at delivery. PA during late pregnancy potentially affects circulating (adipo-)/myokines. Further studies are needed to examine causal relationships and the impact on maternal and new-born health.

Indexed as

ExerciseSedentary BehaviorAdultBody CompositionChildCross-Sectional StudiesFemaleHumansMetabolic EquivalentPregnancyadipokinemyokinephysical activitypregnancy

Identifiers

PMID34948770
PMCPMC8701987
OpenAlexW4200534882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.