Evidence map›Paper›PMID 34948648›Full record

ArticleInternational journal of environmental research and public health2021

Correlation of ADIPOQ Gene Single Nucleotide Polymorphisms with Bone Strength Index in Middle-Aged and the Elderly of Guangxi Mulam Ethnic Group.

Min Zhou, Ning Ning, Yueming Jiang, Michael Aschner, Xiufeng Huang, Xiaoyun Bin, Jinhua Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Min ZhouSchool of Public Health and Management, Youjiang Medical University for Nationalities, Baise 533000, China.
Ning NingSchool of Public Health, Shantou University Medical College, Shantou 515000, China.
Yueming JiangDepartment of Toxicology, School of Public Health, Guangxi Medical University, Nanning 530021, China.
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-2619-1656
Xiufeng HuangSchool of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China.
Xiaoyun BinSchool of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China.
Jinhua WangSchool of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise 533000, China.ORCID 0000-0001-5124-4230
Affiliated Hospital of Youjiang Medical University for Nationalities · CNAlbert Einstein College of Medicine · USGuangxi Medical University · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis (OP) is a common orthopedic disease in the elderly, and Adiponectin (ADIPOQ) is closely related to bone metabolism.

objectiveTo determine the relationship between five single nucleotide polymorphism (SNP) loci in the ADIPOQ gene and osteoporosis in middle-aged and elderly Mulam subjects in Hechi, Guangxi.

methodsThis case-control study included 297 middle-aged and elderly Mulam subjects with normal bone mass, 49 subjects with reduced bone mass, and 38 subjects with osteoporosis. Five loci (

resultsThe bone strength index (SI) of middle-aged and elderly Mulam subjects showed an overall decreasing trend when the subjects were older. Age, muscle mass, and subcutaneous fat content were the main factors influencing the SI in Mulam subjects. The GC genotype of

conclusionsThe GC genotype at

Indexed as

EthnicityPolymorphism, Single NucleotideAdiponectinAgedCase-Control StudiesChinaGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHumansMiddle AgedAdiponectinADIPOQ protein, humanADIPOQbone strength indexmiddle-aged and elderlyMulamosteoporosispolymorphism

Identifiers

PMID34948648
PMCPMC8701406
OpenAlexW4200024519

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.