Evidence map›Paper›PMID 34948431›Full record

ArticleInternational journal of molecular sciences2021

Multi-Omics Reveal the Immunological Role and the Theragnostic Value of miR-216a/GDF15 Axis in Human Colon Adenocarcinoma.

Chun-Bin Tung, Chia-Ying Li, Hung-Yu Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in oncology · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Chun-Bin TungDepartment of Emergency Medicine, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Chia-Ying LiDepartment of Surgery, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
Hung-Yu LinResearch Assistant Center, Show Chwan Memorial Hospital, Changhua 500, Taiwan.ORCID 0000-0002-9035-5408
Chang Bing Show Chwan Memorial Hospital · TWNational Chung Hsing University · TW

Funding

Show Chwan Memorial Hospital, Taiwan SRD-109024 and SRD-109025
6 · The paper itself

Abstract

Colon adenocarcinoma (COAD) is the most common type of gastrointestinal cancer and is still the third leading cause of cancer-related mortality worldwide. Accurate screening tools for early diagnosis and prediction of prognosis and precision treatment strategies are urgently required to accommodate the unmet medical needs of COAD management. We herein aimed to explore the significance of the microRNA (miR)-216a/growth differentiation factor 15 (

Indexed as

Biomarkers, TumorComputational BiologyAdenocarcinomaAntimetabolites, AntineoplasticApoptosisColonic NeoplasmsDeoxycytidineGemcitabineGene Expression Regulation, NeoplasticGrowth Differentiation Factor 15HCT116 CellsHEK293 CellsHumansMicroRNAsMitochondriaPrecision MedicineAntimetabolites, AntineoplasticBiomarkers, TumorDeoxycytidineGDF15 protein, humanGemcitabineGrowth Differentiation Factor 15MicroRNAsMIRN216 microRNA, humancolon adenocarcinomadiagnostic biomarkerGemcitabinegrowth differentiation factor 15immune infiltrationimmunomodulationmiR-216aprecision treatmentprognostic biomarker

Identifiers

PMID34948431
PMCPMC8703770
OpenAlexW4200390610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.