Evidence map›Paper›PMID 34948427›Full record

ArticleInternational journal of molecular sciences2021

KRAS Affects Adipogenic Differentiation by Regulating Autophagy and MAPK Activation in 3T3-L1 and C2C12 Cells.

Wenjie Yu, Cheng-Zhen Chen, Yanxia Peng, Ze Li, Yan Gao, Shuang Liang, Bao Yuan, Nam-Hyung Kim, Hao Jiang, Jia-Bao Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Frontiers in cell and developmental biology · 2024
    Article
  3. Article
  4. Artesunate targets cellular metabolism to regulate the Th17/Treg cell balance.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
  5. Article
  6. Article
  7. Animals : an open access journal from MDPI · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Wenjie YuDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Cheng-Zhen ChenDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Yanxia PengDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Ze LiDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Yan GaoDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Shuang LiangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Bao YuanDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0003-3490-0755
Nam-Hyung KimDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Hao JiangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0003-2008-6166
Jia-Bao ZhangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0001-8533-4744
Jilin University · CNChungbuk National University · KR

Funding

China Agriculture Research System of MOF and MARA CARS-37
6 · The paper itself

Abstract

Kirsten rat sarcoma 2 viral oncogene homolog (

Indexed as

AdipogenesisAutophagyCell ProliferationSignal Transduction3T3 CellsAnimalsCCAAT-Enhancer-Binding Protein-betaCells, CulturedDiacylglycerol O-AcyltransferaseExtracellular Signal-Regulated MAP KinasesFibroblastsGene Expression RegulationJNK Mitogen-Activated Protein KinasesLipid MetabolismMiceMyoblastsCCAAT-Enhancer-Binding Protein-betaCebpb protein, mouseDgat1 protein, mouseDiacylglycerol O-AcyltransferaseExtracellular Signal-Regulated MAP KinasesHras protein, mouseJNK Mitogen-Activated Protein KinasesPPAR gammaProliferating Cell Nuclear AntigenProto-Oncogene Proteins p21(ras)Scd1 protein, mouseStearoyl-CoA DesaturaseTOR Serine-Threonine Kinasesadipogenic differentiationautophagyKRASlipid accumulationMAPKPI3K

Identifiers

PMID34948427
PMCPMC8707842
OpenAlexW4200596956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.