Evidence map›Paper›PMID 34948411›Full record

ReviewInternational journal of molecular sciences2021

Ion Channels and Transporters in Muscle Cell Differentiation.

Lingye Chen, Fatemeh Hassani Nia, Tobias Stauber

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  10. Cardiac selectivity in pulsed field ablation.Current opinion in cardiology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. CaInternational journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Muscle Research: A Tour d'Horizon.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lingye ChenInstitute for Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0002-9877-2118
Fatemeh Hassani NiaInstitute for Molecular Medicine, MSH Medical School Hamburg, 20457 Hamburg, Germany.ORCID 0000-0002-5036-0317
Tobias StauberInstitute for Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.ORCID 0000-0003-0727-6109
MSH Medical School Hamburg – University of Applied Sciences and Medical University · DESun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigations on ion channels in muscle tissues have mainly focused on physiological muscle function and related disorders, but emerging evidence supports a critical role of ion channels and transporters in developmental processes, such as controlling the myogenic commitment of stem cells. In this review, we provide an overview of ion channels and transporters that influence skeletal muscle myoblast differentiation, cardiac differentiation from pluripotent stem cells, as well as vascular smooth muscle cell differentiation. We highlight examples of model organisms or patients with mutations in ion channels. Furthermore, a potential underlying molecular mechanism involving hyperpolarization of the resting membrane potential and a series of calcium signaling is discussed.

Indexed as

Muscle DevelopmentAnimalsCell DifferentiationHumansIon ChannelsMembrane Transport ProteinsMuscle, SkeletalMuscle, Smooth, VascularMyoblastsMyocytes, CardiacPluripotent Stem CellsIon ChannelsMembrane Transport Proteinsbioelectricitycalcium signalingcardiac differentiationmembrane potentialmyoblast differentiationstem cellsvascular remodeling

Identifiers

PMID34948411
PMCPMC8703453
OpenAlexW4200529332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.