Evidence map›Paper›PMID 34948397›Full record

ArticleInternational journal of molecular sciences2021

Magnesium and Morphine in the Treatment of Chronic Neuropathic Pain-A Biomedical Mechanism of Action.

Kamila Kulik, Barbara Żyżyńska-Granica, Agnieszka Kowalczyk, Przemysław Kurowski, Małgorzata Gajewska, Magdalena Bujalska-Zadrożny

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Nanoparticulate MgHMolecular pain
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kamila KulikCentre for Preclinical Research and Technology, Department of Pharmacodynamics, Medical University of Warsaw, Banacha 1b Str., 02-097 Warsaw, Poland.
Barbara Żyżyńska-GranicaCentre for Preclinical Research and Technology, Department of Pharmacodynamics, Medical University of Warsaw, Banacha 1b Str., 02-097 Warsaw, Poland.ORCID 0000-0002-1641-0018
Agnieszka KowalczykCentre for Preclinical Research and Technology, Department of Pharmacodynamics, Medical University of Warsaw, Banacha 1b Str., 02-097 Warsaw, Poland.
Przemysław KurowskiCentre for Preclinical Research and Technology, Department of Pharmacodynamics, Medical University of Warsaw, Banacha 1b Str., 02-097 Warsaw, Poland.ORCID 0000-0001-5577-0115
Małgorzata GajewskaDepartment of Physiological Sciences, Warsaw University of Life Sciences, Nowoursynowska 159 Str., 02-776 Warsaw, Poland.ORCID 0000-0001-7249-8627
Magdalena Bujalska-ZadrożnyCentre for Preclinical Research and Technology, Department of Pharmacodynamics, Medical University of Warsaw, Banacha 1b Str., 02-097 Warsaw, Poland.
Medical University of Warsaw · PLWarsaw University of Life Sciences · PL

Funding

Medical University of Warsaw FW3/PM3/16; FW3/PM4/16
6 · The paper itself

Abstract

The effectiveness of opioids in the treatment of neuropathic pain is limited. It was demonstrated that magnesium ions (Mg

Indexed as

Analgesics, OpioidAnimalsMagnesiumMaleMorphineNeuralgiaPhosphorylationProtein Kinase CRatsRats, WistarReceptors, N-Methyl-D-AspartateReceptors, Opioid, muAnalgesics, OpioidMagnesiumMorphineProtein Kinase CReceptors, N-Methyl-D-AspartateReceptors, Opioid, muanalgesiamagnesiummorphineneuropathic ratsN-methyl-D-aspartate receptorreceptor associationµ-opioid receptor

Identifiers

PMID34948397
PMCPMC8707930
OpenAlexW4200177234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.