Evidence map›Paper›PMID 34948362›Full record

ArticleInternational journal of molecular sciences2021

Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA.

Kristin Oepen, Hüseyin Özbek, Anja Schüffler, Johannes C Liermann, Eckhard Thines, Dirk Schneider

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. The Antidepressant Drug Clomipramine Inhibits the ABC Transporter BmrA.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kristin OepenDepartment of Chemistry, Johannes Gutenberg-University, 55128 Mainz, Germany.
Hüseyin ÖzbekInstitut für Biotechnologie und Wirkstoff-Forschung gGmbH (IBWF), 55128 Mainz, Germany.
Anja SchüfflerInstitut für Biotechnologie und Wirkstoff-Forschung gGmbH (IBWF), 55128 Mainz, Germany.ORCID 0000-0002-0819-4300
Johannes C LiermannDepartment of Chemistry, Johannes Gutenberg-University, 55128 Mainz, Germany.
Eckhard ThinesInstitut für Biotechnologie und Wirkstoff-Forschung gGmbH (IBWF), 55128 Mainz, Germany.
Dirk SchneiderDepartment of Chemistry, Johannes Gutenberg-University, 55128 Mainz, Germany.ORCID 0000-0003-4517-6387
Johannes Gutenberg University Mainz · DEInstitut für Biotechnologie und Wirkstoff-Forschung · DE

Funding

DynaMem (State of Rhineland-Palatinate) N/ANaturwissenschaftlich-Medizinisches Forschungszentrum (NMFZ) Mainz N/A
6 · The paper itself

Abstract

ATP-binding cassette (ABC) transporters are conserved in all kingdoms of life, where they transport substrates against a concentration gradient across membranes. Some ABC transporters are known to cause multidrug resistances in humans and are able to transport chemotherapeutics across cellular membranes. Similarly, BmrA, the ABC transporter of

Indexed as

Adenosine TriphosphatasesATP-Binding Cassette TransportersBacillus subtilisBacterial ProteinsDrug DiscoveryMyristic AcidAdenosine TriphosphatasesATP-Binding Cassette TransportersBacterial ProteinsMyristic AcidABC transporterBmrAinhibitormembrane transportmyristic acid

Identifiers

PMID34948362
PMCPMC8707315
OpenAlexW4200002599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.